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| Content Provider | frontiers |
|---|---|
| Author | Wu, Yuhao Li, Jiashan Wu, Chun Zhu, Jin He, Ling Feng, Chuan Yang, Yiting Jin, Xin |
| Abstract | Introduction: This study aims to summarize the clinical characteristics of coarctation of the aorta (CoA) associated with intracardiac anomalies in infants.Methods: Medical records of 93 infants who were diagnosed with CoA and intracardiac anomalies from August 2009 to August 2018 were retrospectively reviewed.Results: All of the 93 infants underwent single-stage repair for CoA associated with intracardiac anomalies. The mean operative time was 264.6 ± 57.1 min, and the time of ICU stay was 7.0 ± 4.1 days. The residual transcoarctation pressure gradient before discharge was lower than the pressure gradient prior to surgery (48.3 ± 17.5 vs. 22.4 ± 9.6 mmHg, P < 0.01). Early death before discharge was found in five infants. The mean follow-up time of 88 hospital survivors was 40.0 ± 26.4 months, and no subsequent death occurred in the follow-up. Transcoarctation pressure gradient of the 88 survivors in their last follow-up was 19.6 ± 10.5 mmHg. The pressure gradient of 27 cases was higher than 20 mmHg. Significant lower limb retardation was observed in four cases; therefore, balloon angioplasty consult was recommended. The cumulative recoarctation-free survival rate in 3-year follow-up was 73.5%.Conclusions: To avoid secondary operations in early period, single-stage repair of CoA associated with intracardiac anomalies was effective and safe, and the outcomes in early to mid-term follow-up were satisfactory. |
| ISSN | 22962360 |
| DOI | 10.3389/fped.2020.00049 |
| Volume Number | 8 |
| Journal | Frontiers in Pediatrics |
| Language | English |
| Publisher Date | 2020-03-03 |
| Access Restriction | Open |
| Subject Keyword | Pathol ogy Infants (human) Congenital heart disease - cardiac Surgery Coarctation of the aorta (COA) |
| Content Type | Text |
| Resource Type | Article |
| Subject | Pediatrics, Perinatology and Child Health |
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