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| Content Provider | frontiers |
|---|---|
| Author | Li, Han Zhao, Meng Fei, Gaoqiang Wang, Zemin Wang, Shuai Wei, Pingmin Li, Wei |
| Abstract | Lung cancer remains the most common malignancy in China. This study aims to provide scientific support for the prevention and treatment of lung cancer by analyzing the epidemiological trends of lung cancer in China from 1990 to 2019. Based on the global health exchange database (GHDx), joinpoint and age-period-cohort analyses were performed to explore the trend of lung cancer incidence and mortality rates from 1990 to 2019. According to incidence rates from 1990 to 2019, a model was constructed to predict the incidence rates in the next five years. In addition, changes in risk factors associated with lung cancer deaths were compared between 1990 and 2019 and between males and females in 2019.The results are as follows. The age-standardized incidence rates (ASIRs), age-standardized death rates (ASDRs) of lung cancer among Chinese had overall upward trends from 1990 to 2019. The ASDRs of females and males in China decreased since 2010. Interestingly, from 2016 to 2019, the ASIRs and ASDRs of females rose significantly. The age-period-cohort model showed that the incidence and mortality rates of lung cancer in China increased with age, and the growth rate accelerated after the 45 years old. After 2004, the relative risks of lung cancer incidence increased with the passage of period. Also, after 1950-1954 birth cohort, the risks of lung cancer incidence and death began decreased. The autoregressive integrated moving average model (AIRMA) model predicted that the incidence rates of lung cancer in China would continue to rise in the next five years. Smoking, ambient particulate matter pollution, household air pollution from solid fuels, secondhand smoke, high fasting plasma remain major risk factors for lung cancer deaths. The above results provided precise clues for the prevention and treatment of lung cancer in China. |
| ISSN | 2296858X |
| DOI | 10.3389/fmed.2022.969487 |
| Volume Number | 9 |
| Journal | Frontiers in Medicine |
| Language | English |
| Publisher Date | 2022-09-20 |
| Access Restriction | Open |
| Subject Keyword | Lung cancer Prediction China Epidemiological trends Global Burden of Disease study |
| Content Type | Text |
| Resource Type | Article |
| Subject | Medicine |
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