Please wait, while we are loading the content...
| Content Provider | frontiers |
|---|---|
| Author | Cao, Longxiang Zhou, Jing Chen, Mingzhi Chen, Tao Liu, Man Mao, Wenjian Lin, Jiyan Hong, Donghuang Yao, Weijie Sun, Yi Qin, Kaixiu Guo, Feng Zhou, Yun Jiao, Qinghai Chen, Yingjie Li, Gang Ye, Bo Ke, Lu Tong, Zhihui Liu, Yuxiu Li, Weiqin |
| Organization | Chinese Acute Pancreatitis Clinical Trials Group (CAPCTG) |
| Abstract | Background: Acute pancreatitis is a potentially life-threatening inflammatory disease with multiple etiologies. The prevalence of hypertriglyceridemia-induced acute pancreatitis (HTG-AP) had been increased in recent years. It is reported that early triglyceride (TG) levels were associated with the severity of the disease, and TG lowering therapies, including medical treatment and blood purification, may impact the clinical outcomes. However, there is no consensus regarding the optimal TG-lower therapy, and clinical practice varies greatly among different centers. Our objective is to evaluate the TG-lowering effects of different therapies and their impact on clinical outcomes in patients with predicted severe HTG-AP. Methods: This is a multicenter, observational, prospective, cohort study. A total of approximately 290 patients with predicted severe HTG-AP are planned to be enrolled. The primary outcome is organ failure (OF) free days to 14 days after enrollment. Secondary outcomes include new-onset organ failure, CT severity score, level of TG, ICU free days to 14 days after enrollment, 60-day mortality, etc. Generalized linear model (GLM), Fine and Gray competing risk regression, and propensity score matching will be used for statistical analysis. Discussion: Results of this study will reveal the current practice of TG-lowering therapy in HTG-AP and provide necessary data for future trials. Clinical trial registration: Registered at https://www.chictr.org.cn/index.aspx. Trial registration number: ChiCTR2000039541 |
| ISSN | 2296858X |
| DOI | 10.3389/fmed.2021.756337 |
| Volume Number | 8 |
| Journal | Frontiers in Medicine |
| Language | English |
| Publisher Date | 2021-12-13 |
| Access Restriction | Open |
| Subject Keyword | Acute pancreatitis (AP) Cohort study Hypertriglyceridemia (HTG) TG-lowering therapy Organ failure free day |
| Content Type | Text |
| Resource Type | Article |
| Subject | Medicine |
National Digital Library of India (NDLI) is a virtual repository of learning resources which is not just a repository with search/browse facilities but provides a host of services for the learner community. It is sponsored and mentored by Ministry of Education, Government of India, through its National Mission on Education through Information and Communication Technology (NMEICT). Filtered and federated searching is employed to facilitate focused searching so that learners can find the right resource with least effort and in minimum time. NDLI provides user group-specific services such as Examination Preparatory for School and College students and job aspirants. Services for Researchers and general learners are also provided. NDLI is designed to hold content of any language and provides interface support for 10 most widely used Indian languages. It is built to provide support for all academic levels including researchers and life-long learners, all disciplines, all popular forms of access devices and differently-abled learners. It is designed to enable people to learn and prepare from best practices from all over the world and to facilitate researchers to perform inter-linked exploration from multiple sources. It is developed, operated and maintained from Indian Institute of Technology Kharagpur.
Learn more about this project from here.
NDLI is a conglomeration of freely available or institutionally contributed or donated or publisher managed contents. Almost all these contents are hosted and accessed from respective sources. The responsibility for authenticity, relevance, completeness, accuracy, reliability and suitability of these contents rests with the respective organization and NDLI has no responsibility or liability for these. Every effort is made to keep the NDLI portal up and running smoothly unless there are some unavoidable technical issues.
Ministry of Education, through its National Mission on Education through Information and Communication Technology (NMEICT), has sponsored and funded the National Digital Library of India (NDLI) project.
| Sl. | Authority | Responsibilities | Communication Details |
|---|---|---|---|
| 1 | Ministry of Education (GoI), Department of Higher Education |
Sanctioning Authority | https://www.education.gov.in/ict-initiatives |
| 2 | Indian Institute of Technology Kharagpur | Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project | https://www.iitkgp.ac.in |
| 3 | National Digital Library of India Office, Indian Institute of Technology Kharagpur | The administrative and infrastructural headquarters of the project | Dr. B. Sutradhar bsutra@ndl.gov.in |
| 4 | Project PI / Joint PI | Principal Investigator and Joint Principal Investigators of the project |
Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon |
| 5 | Website/Portal (Helpdesk) | Queries regarding NDLI and its services | support@ndl.gov.in |
| 6 | Contents and Copyright Issues | Queries related to content curation and copyright issues | content@ndl.gov.in |
| 7 | National Digital Library of India Club (NDLI Club) | Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach | clubsupport@ndl.gov.in |
| 8 | Digital Preservation Centre (DPC) | Assistance with digitizing and archiving copyright-free printed books | dpc@ndl.gov.in |
| 9 | IDR Setup or Support | Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops | idr@ndl.gov.in |
|
Loading...
|