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| Content Provider | frontiers |
|---|---|
| Author | Diao, Jiuzhou Zhou, Qingbo |
| Description | A case of a 15-ages girl with Avermectin Pyridine poisoning is reported here. This pesticide poisoning common symptoms involve nausea and vomiting shock, respiratory failure, nausea and vomiting, and showed varying degrees of neurological damage. The characteristics of this case and its significance lie in the simultaneous involvement of the central and peripheral nervous systems and the patient completely recovered after treatment with mechanical ventilation, hemodialysis, hormone, hyperbaric oxygen therapy and neurotrophic therapies. In addition, seven other cases of similar poisoning are also discussed to provide experience for clinical treatment. |
| Abstract | BackgroundAvermectin Pyridaben (AVP) is an insecticide with extreme neurotoxicity in human, causing critical symptoms such as nausea, vomiting, coma and respiratory failure within a short time after oral ingestion. Neurological sequelae or even death may occur because of delayed treatment or excessive toxic dose.Case presentationWe report a 15-year-old girl who presented with coma, respiratory failure, limb weakness, ataxia symptoms after ingestion of a toxic dose of AVP. Soon after the poisoning, the patient was treated with life-saving mechanical ventilation and haemodialysis. Subsequently brain Magnetic Resonance Imaging (MRI) and nerve conduction study (NCS) and electromyography (EMG) demonstrated toxic encephalopathy and peripheral nerve injury. Over the next 2 months the patient’s limb function gradually recovered under treatment with hyperbaric oxygen, glucocorticoid pulses and neurotrophic drugs.ConclusionThis case documents a rare presentation of toxic encephalopathy complicated with peripheral neuropathy following AVP poisoning. Seven other similar cases of poisoning in terms of common symptoms and effective treatment have also been summarised for providing clinicians with experience in diagnosis and therapy. |
| ISSN | 16642295 |
| DOI | 10.3389/fneur.2023.1144970 |
| Volume Number | 14 |
| Journal | Frontiers in Neurology |
| Language | English |
| Publisher Date | 2023-06-02 |
| Access Restriction | Open |
| Subject Keyword | Toxic encephalopathy Avermectin and Pyridine Peripheral neuropathy Therapy Case report |
| Content Type | Text |
| Resource Type | Article |
| Subject | Neurology Neurology (clinical) |
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