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| Content Provider | frontiers |
|---|---|
| Author | Holderer, O. Koutsioubas, A. Garvey, C. J. Nylander, T. |
| Abstract | Self-assembled phospholipid bilayers are ubiquitous in biology and chemistry. In biological systems they constitute membranes that act as cell barriers that mediate the exchange of compounds, energy and information with the extra-cellular environement and essentially act as a host for membrane proteins that carry out a multitude of critical taks. In modern chemistry, self-assembled surfactant or lipid membranes in dispersed lamellar or non-lamellar phases (cubic and hexagonal) or bicontinuous microemulsions are frequently used in health care or consumer products to encapsulate and deliver active substances for controlled pharmacokinetics. Thanks to their generally well defined structure and properties, and using nature as an inspiration they can also be used to formulate nano-scale reactors for sustainable synthesis.Neutron scattering provides a unique view on nanoscopic and mesoscopic structure of self-assembled membranes, for example with Small Angle Neutron Scattering (SANS) in solution or with Neutron Reflectivity (NR) using contrast variation through deuterium labelling. Thermal membrane fluctuations are measured with Neutron Spin Echo (NSE) spectroscopy, allowing us to study how changes in environment, for example adding diblock copolymers or changing solvent properties, can influence membrane elasticity. Recent advances in instrumentation have also provided access to membrane dynamics at the solid-liquid interface with grazing incidence NSE (GINSES).Contrast variati... |
| ISSN | 22962646 |
| DOI | 10.3389/fchem.2021.732062 |
| Volume Number | 9 |
| Journal | Frontiers in Chemistry |
| Language | English |
| Publisher Date | 2021-08-19 |
| Access Restriction | Open |
| Subject Keyword | Microemulsions Reflectometry Bending elasticity Small angle neutron scattering Lipid membranes Neutron spin echo Neutron scattering |
| Content Type | Text |
| Resource Type | Article |
| Subject | Chemistry |
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