Loading...
Please wait, while we are loading the content...
Similar Documents
Changes in body weight and glycemic control in association with COVID-19 Shutdown among 23,000 adults with type 2 diabetes.
| Content Provider | Europe PMC |
|---|---|
| Author | Panza, Emily Kip, Kevin E. Venkatakrishnan, Kripa Marroquin, Oscar C. Wing, Rena R. |
| Abstract | AimsTo examine the association between COVID-19 Shutdown and within-subjects changes in body weight, body mass index (BMI), and glycemic parameters using electronic health record (EHR) data from 23,000 adults with type 2 diabetes (T2DM).MethodsPatients with T2DM with outpatient visit data on body weight, BMI, hemoglobin A1c (HbA1c), and blood glucose (≥ 2 measures before and after 3/16/2020) recorded in the EHR at the University of Pittsburgh Medical Center were included. A within-subjects analysis compared average and clinically significant changes in weight, BMI, HbA1c, and blood glucose during the year POST-Shutdown (Time 2–3) compared to the same interval during the PRE-Shutdown year (Time 0–1) using paired samples t-tests and the McNemar-Bowker test.ResultsWe studied 23,697 adults with T2DM (51% female; 89% White; mean age = 66 ± 13 years; mean BMI = 34 ± 7 kg/m2; mean HbA1c = 7 ± 2% [53 ± 21.9 mmol/mol]). Weight and BMI decreased during both the PRE- and POST-Shutdown intervals, but the changes were statistically smaller during the year POST-Shutdown relative to PRE (0.32 kg and 0.11 units, p < 0.0001). HbA1c showed statistically greater improvements during the POST-Shutdown interval compared to PRE (− 0.18% [−2 mmol/mol], p < 0.0001), but changes in glucose did not differ for the two intervals.ConclusionsDespite widespread discussion of weight gain in association with the COVID-19 Shutdown, study data showed no evidence of adverse effects of Shutdown on body weight, BMI, HbA1C, or blood glucose in a large sample of adults with T2DM. This information may help to inform future public health decision-making.Supplementary InformationThe online version contains supplementary material available at 10.1007/s00592-023-02056-5. |
| Related Links | https://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC9998005&blobtype=pdf |
| ISSN | 09405429 |
| Journal | Acta Diabetologica [Acta Diabetol] |
| Volume Number | 60 |
| DOI | 10.1007/s00592-023-02056-5 |
| PubMed Central reference number | PMC9998005 |
| Issue Number | 6 |
| PubMed reference number | 36894712 |
| e-ISSN | 14325233 |
| Language | English |
| Publisher | Springer Milan |
| Publisher Date | 2023-03-09 |
| Publisher Place | Milan |
| Access Restriction | Open |
| Rights License | This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic. © Springer-Verlag Italia S.r.l., part of Springer Nature 2023, Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law. |
| Subject Keyword | Weight change Metabolic effects Pandemic COVID-19 Type 2 diabetes |
| Content Type | Text |
| Resource Type | Article |
| Subject | Endocrinology, Diabetes and Metabolism Internal Medicine Endocrinology |
