NDLI: Carcinoembryonic Antigen, Carbohydrate Antigen 19-9, Cancer Antigen 125, Prostate-Specific Antigen and Other Cancer Markers: A Primer on Commonly Used Cancer Markers.

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Carcinoembryonic Antigen, Carbohydrate Antigen 19-9, Cancer Antigen 125, Prostate-Specific Antigen and Other Cancer Markers: A Primer on Commonly Used Cancer Markers.

Content Provider	Europe PMC
Author	Desai, Shreya Guddati, Achuta K.
Copyright Year	2023
Abstract	Cancer markers are molecules produced by cancer cells which may serve to identify the presence of cancer. Cancer markers can be differentiated as serum-based, radiology-based and tissue-based, and are one of the most important tools in diagnosing, staging and monitoring of treatment of many cancers. The most used cancer markers are serum cancer markers due to its relative ease and lower cost of testing. However, serum cancer markers have poor mass screening utilization due to poor positive predictive value. Several markers such as prostate-specific antigen (PSA), beta-human chorionic gonadotropin (B-hCG), alpha-fetoprotein (AFP), and lactate dehydrogenase (LDH) are used to aid in diagnosis of cancer in cases of high suspicion. Serum markers such as carcinoembryonic antigen (CEA), AFP, carbohydrate antigen 19-9 (CA 19-9), and 5-hydroxyindoleacetic acid (5-HIAA) play a significant role in assessing disease prognosis as well as response to treatment. This work reviews the role of some of the biomarkers in the diagnosis and treatment of cancer.
Related Links	https://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC9990734&blobtype=pdf
ISSN	19204531
Journal	World Journal of Oncology [World J Oncol]
Volume Number	14
DOI	10.14740/wjon1425
PubMed Central reference number	PMC9990734
Issue Number	1
PubMed reference number	36895994
e-ISSN	1920454X
Language	English
Publisher	Elmer Press
Publisher Date	2023-02-26
Access Restriction	Open
Rights License	This article is distributed under the terms of the Creative Commons Attribution Non-Commercial 4.0 International License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. Copyright 2023, Desai et al.
Subject Keyword	Tumor markers Serum markers CA 19-9 CEA AFP Cancer screening Prognostic markers CA-125 PSA CA 27-29 B-hCG Calcitonin 5-HIAA LDH
Content Type	Text
Resource Type	Article
Subject	Cancer Research Oncology

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