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Optical Coherence Tomography Angiography for Detecting Nonexudative Macular Neovascularization in Age-Related Macular Degeneration.
| Content Provider | Europe PMC |
|---|---|
| Author | Greenberg, Jeremy R. Kim, Brian Y. Brady, Christopher J. Millay, Robert H. Raut, Robert |
| Copyright Year | 2022 |
| Description | Purpose: To compare the efficacy of optical coherence tomography angiography (OCTA) and indocyanine green angiography (ICGA) for detecting nonexudative macular neovascularization (MNV) in age-related macular degeneration (AMD). Methods: In this prospective study, patients with a new diagnosis of exudative AMD in 1 eye were imaged using OCTA, fluorescein angiography (FA), and ICGA in both eyes. The rates at which these imaging modalities detected nonexudative MNV in the nonexudative fellow eye were then compared. Results: This study comprised 41 eyes with a mean follow-up was 14 months. Nonexudative MNV was found in 3 eyes using OCTA and ICGA. No MNV exudation was detected on FA or structural OCT. One of 3 eyes with MNV progressed to exudative disease 6 months after the initial visit. During the follow-up, 5 of the 38 eyes without MNV developed exudation at 4 to 18 months. Conclusions: OCTA is similarly effective as ICGA at detecting nonexudative MNV patterns. |
| Abstract | Purpose: To compare the efficacy of optical coherence tomography angiography (OCTA) andindocyanine green angiography (ICGA) for detecting nonexudative macularneovascularization (MNV) in age-related macular degeneration (AMD). Methods: In this prospective study, patients with a new diagnosis of exudative AMD in 1 eye wereimaged using OCTA, fluorescein angiography (FA), and ICGA in both eyes. The rates atwhich these imaging modalities detected nonexudative MNV in the nonexudative fellow eyewere then compared. Results: This study comprised 41 eyes with a mean follow-up was 14 months. Nonexudative MNV wasfound in 3 eyes using OCTA and ICGA. No MNV exudation was detected on FA or structuralOCT. One of 3 eyes with MNV progressed to exudative disease 6 months after the initialvisit. During the follow-up, 5 of the 38 eyes without MNV developed exudation at 4 to 18months. Conclusions: OCTA is similarly effective as ICGA at detecting nonexudative MNV patterns. |
| Related Links | https://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC9954158&blobtype=pdf |
| ISSN | 24741264 |
| Volume Number | 7 |
| DOI | 10.1177/24741264221126297 |
| PubMed Central reference number | PMC9954158 |
| Issue Number | 1 |
| PubMed reference number | 37008398 |
| Journal | Journal of Vitreoretinal Diseases [J Vitreoretin Dis] |
| e-ISSN | 24741272 |
| Language | English |
| Publisher | SAGE Publications |
| Publisher Date | 2022-12-09 |
| Publisher Place | Sage CA: Los Angeles, CA |
| Access Restriction | Open |
| Rights License | © The Author(s) 2022 |
| Subject Keyword | age-related macular degeneration fluorescein angiography indocyanine green angiography macular neovascularization nonexudative optical coherence tomography angiography subclinical |
| Content Type | Text |
| Resource Type | Article |
| Subject | Ophthalmology |
