Se-Enriched Cardamine violifolia Improves Laying Performance and Regulates Ovarian Antioxidative Function in Aging Laying Hens.

Content Provider	Europe PMC
Author	Wang, Hui Cong, Xin Qin, Kun Yan, Mengke Xu, Xianfeng Liu, Mingkang Xu, Xiao Zhang, Yue Gao, Qingyu Cheng, Shuiyuan Zhao, Jiangchao Zhu, Huiling Liu, Yulan
Editor	Bergamo, Paolo
Copyright Year	2023
Abstract	As a selenium-enriched plant, Cardamine violifolia (SEC) has an excellent antioxidant function. The edibility of SEC is expected to develop new sources of organic Se supplementation for human and animal nutrition. This study was conducted to investigate the effects of SEC on laying performance and ovarian antioxidant capacity in aging laying hens. A total of 450 laying hens were assigned to five treatments. Dietary treatments included the following: a basal diet (diet without Se supplementation, CON) and basal diets supplemented with 0.3 mg/kg Se from sodium selenite (SS), 0.3 mg/kg Se from Se-enriched yeast (SEY), 0.3 mg/kg Se from SEC, or 0.3 mg/kg Se from SEC and 0.3 mg/kg Se from SEY (SEC + SEY). Results showed that supplementation with SEC tended to increase the laying rate, increased the Haugh unit of eggs, and reduced the FCR. SEC promoted ovarian cell proliferation, inhibited apoptosis, and ameliorated the maintenance of follicles. SEC, SEY, or SEC + SEY increased ovarian T-AOC and decreased MDA levels. SEC increased the mRNA abundance of ovarian selenoproteins. SEC and SEC + SEY increased the mRNA abundance of Nrf2, HO-1, and NQO1, and decreased the mRNA abundance of Keap1. These results indicate that SEC could potentially to improve laying performance and egg quality via the enhancement of ovarian antioxidant capacity. SEC exerts an antioxidant function through the modulation of the Nrf2/Keap1 signaling pathway.
Journal	Antioxidants (Basel, Switzerland)
Volume Number	12
PubMed Central reference number	PMC9952132
Issue Number	2
PubMed reference number	36830007
e-ISSN	20763921
DOI	10.3390/antiox12020450
Language	English
Publisher	MDPI
Publisher Date	2023-02-10
Access Restriction	Open
Rights License	Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). © 2023 by the authors.
Subject Keyword	Cardamine violifolia hens selenium ovary laying performance antioxidant
Content Type	Text
Resource Type	Article
Subject	Biochemistry Cell Biology Molecular Biology Physiology Clinical Biochemistry Food Science