Tuning Photochemical and Photophysical Properties of P(V) Phthalocyanines.

Content Provider	Europe PMC
Author	Safonova, Evgeniya A. Kolomeychuk, Filipp M. Gvozdev, Daniil A. Tsivadze, Aslan Yu. Gorbunova, Yulia G.
Editor	Senge, Mathias O.
Copyright Year	2023
Abstract	The ability of P(V) phthalocyanines (Pcs) for efficient singlet oxygen (SO) generation was demonstrated for the first time by the example of unsubstituted and α- and β-octabutoxy-substituted P(V)Pcs with hydroxy, methoxy and phenoxy ligands in the apical positions of the octahedral P centre. Variation of substituents in Pc ring and P(V) axial ligands allows careful tuning of photophysical and photochemical properties. Indeed, a combination of BuO groups in the β-positions of the Pc ring and PhO groups as axial ligands provides significant SO generation quantum yields up to 90%; meanwhile, the values of SO generation quantum yields for others investigated compounds vary from 27 to 55%. All the complexes, except α-substituted P(V)Pc, demonstrate fluorescence with moderate quantum yields (10-16%). The introduction of electron-donating butoxy groups, especially in the α-position, increases the photostability of P(V)Pcs. Moreover, it has been shown in the example of β-BuO-substituted P(V) that the photostability depends on the nature of axial ligands and increases in the next row: OPh < OMe < OH. The presence of oxy/hydroxy axial ligands on the P(V) atom makes it possible to switch the photochemical and photophysical properties of P(V)Pcs by changing the acidity of the media.
Journal	Molecules
Volume Number	28
DOI	10.3390/molecules28031094
PubMed Central reference number	PMC9920145
Issue Number	3
PubMed reference number	36770759
e-ISSN	14203049
Language	English
Publisher	Molecular Diversity Preservation International (MDPI)
Publisher Date	2023-01-21
Access Restriction	Open
Subject Keyword	phthalocyanine phosphorus fluorescence singlet oxygen photostability
Content Type	Text
Resource Type	Article
Subject	Physical and Theoretical Chemistry Medicine Chemistry Drug Discovery Pharmaceutical Science Analytical Chemistry Molecular Medicine Organic Chemistry