Molecularly Imprinted Polymer-Based Sensors for Protein Detection.

Content Provider	Europe PMC
Author	Akgönüllü, Semra Kılıç, Seçkin Esen, Cem Denizli, Adil
Editor	Kim, Beom Soo
Copyright Year	2023
Abstract	The accurate detection of biological substances such as proteins has always been a hot topic in scientific research. Biomimetic sensors seek to imitate sensitive and selective mechanisms of biological systems and integrate these traits into applicable sensing platforms. Molecular imprinting technology has been extensively practiced in many domains, where it can produce various molecular recognition materials with specific recognition capabilities. Molecularly imprinted polymers (MIPs), dubbed plastic antibodies, are artificial receptors with high-affinity binding sites for a particular molecule or compound. MIPs for protein recognition are expected to have high affinity via numerous interactions between polymer matrices and multiple functional groups of the target protein. This critical review briefly describes recent advances in the synthesis, characterization, and application of MIP-based sensor platforms used to detect proteins.
Journal	Polymers
Volume Number	15
PubMed Central reference number	PMC9919373
Issue Number	3
PubMed reference number	36771930
e-ISSN	20734360
DOI	10.3390/polym15030629
Language	English
Publisher	MDPI
Publisher Date	2023-01-26
Access Restriction	Open
Rights License	Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). © 2023 by the authors.
Subject Keyword	molecularly imprinted polymers protein detection molecular imprinting sensors biomolecules nanofilm
Content Type	Text
Resource Type	Article
Subject	Chemistry Polymers and Plastics