NDLI: Mesenchymal Stem Cells and Their Exocytotic Vesicles.

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Mesenchymal Stem Cells and Their Exocytotic Vesicles.

Content Provider	Europe PMC
Author	Cai, Hao Guo, Haidong
Editor	Oliva, Joan
Copyright Year	2023
Abstract	Mesenchymal stem cells (MSCs), as a kind of pluripotent stem cells, have attracted much attention in orthopedic diseases, geriatric diseases, metabolic diseases, and sports functions due to their osteogenic potential, chondrogenic differentiation ability, and adipocyte differentiation. Anti-inflammation, anti-fibrosis, angiogenesis promotion, neurogenesis, immune regulation, and secreted growth factors, proteases, hormones, cytokines, and chemokines of MSCs have been widely studied in liver and kidney diseases, cardiovascular and cerebrovascular diseases. In recent years, many studies have shown that the extracellular vesicles of MSCs have similar functions to MSCs transplantation in all the above aspects. Here we review the research progress of MSCs and their exocrine vesicles in recent years.
Journal	International Journal of Molecular Sciences [Int J Mol Sci]
Volume Number	24
DOI	10.3390/ijms24032085
PubMed Central reference number	PMC9916886
Issue Number	3
PubMed reference number	36768406
e-ISSN	14220067
Language	English
Publisher	Molecular Diversity Preservation International (MDPI)
Publisher Date	2023-01-20
Access Restriction	Open
Subject Keyword	mesenchymal stem cells differentiation extracellular vesicles immunomodulation cardiocerebral diseases signaling pathways
Content Type	Text
Resource Type	Article
Subject	Physical and Theoretical Chemistry Molecular Biology Spectroscopy Catalysis Computer Science Applications Medicine Inorganic Chemistry Organic Chemistry

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