NDLI: Copper(I)-Catalyzed Alkyne-Azide Cycloaddition (CuAAC) "Click" Reaction: A Powerful Tool for Functionalizing Polyhydroxylated Platforms.

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Copper(I)-Catalyzed Alkyne-Azide Cycloaddition (CuAAC) "Click" Reaction: A Powerful Tool for Functionalizing Polyhydroxylated Platforms.

Content Provider	Europe PMC
Author	Pineda-Castañeda, HéctorManuel Rivera-Monroy, Zuly Jenny Maldonado, Mauricio
Copyright Year	2023
Abstract	Click chemistry iscurrently one of the most used tools for thegeneration of complex organic molecules. The advantages of using clickchemistry in organic synthesis are remarkable; in many cases, thereactions occur under mild conditions and are free of solvents, withhigh yields and short reaction times. This makes it an extraordinarilyeffective and viable alternative for obtaining complex/conjugatedmolecules. In this review, the use of click chemistry CuAAC is especiallyemphasized for polyhydroxylated platforms such as resorcinarenes orcalixarenes, focusing mainly on aspects of synthesis, specificallyconditions, reagents, and methodologies.
Journal	ACS Omega
Volume Number	8
PubMed Central reference number	PMC9893463
Issue Number	4
PubMed reference number	36743057
e-ISSN	24701343
DOI	10.1021/acsomega.2c06269
Language	English
Publisher	American Chemical Society
Publisher Date	2023-01-18
Access Restriction	Open
Rights License	Permits non-commercial access and re-use, provided that author attribution and integrity are maintained; but does not permit creation of adaptations or other derivative works (https://creativecommons.org/licenses/by-nc-nd/4.0/). © 2023 The Authors. Published by American Chemical Society
Content Type	Text
Resource Type	Article
Subject	Chemistry Chemical Engineering

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