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Sugar Sweetened and Artificially Sweetened Beverage Consumption and Pancreatic Cancer: A Retrospective Study.
| Content Provider | Europe PMC |
|---|---|
| Author | Davis, Evan W. McCann, Susan E. Joseph, Janine M. Yeary, Karen H. K. Fountzilas, Christos Moysich, Kirsten B. |
| Editor | Pekmezi, Dorothy Benitez, Tanya Brunetti, Antonio |
| Copyright Year | 2023 |
| Abstract | Pancreatic cancer (PanCa) is a highly fatal malignancy with few modifiable risk and prognostic factors. This study investigates the association between cola, diet cola, and non-cola soft drink consumption and PanCa risk and mortality. A retrospective study was conducted using data from the Patient Epidemiology Data System (1982–1998) at Roswell Park Comprehensive Cancer Center (Buffalo, NY, USA), including 213 PanCa patients and 852 cancer-free controls. Data were collected using a self-administered questionnaire, including a 46-item food frequency questionnaire (FFQ). Multivariable logistic regression was used to estimate odds ratio (OR) and 95% confidence interval (CI) of cola, diet cola, and non-cola soft drink consumption and PanCa risk. Cox proportional hazard regression was used to estimate hazard ratios (HR) and 95% CIs of cola, diet cola, and non-cola soft drink consumption and PanCa mortality. Stratified analyses were conducted by sex, body mass index (BMI), and smoking status. We observed significant 55% increased odds of PanCa among patients consuming ≥1 regular cola per day (OR: 1.55, 95% CI: 1.01–2.39). We also observed non-significant 38% increased hazard of mortality among patients consuming ≥1 regular cola per day (HR: 1.38, 95% CI: 0.91–2.07). We conclude that regular cola consumption is a modifiable lifestyle that may be associated with PanCa risk and mortality following diagnosis. |
| Journal | Nutrients |
| Volume Number | 15 |
| PubMed Central reference number | PMC9866356 |
| Issue Number | 2 |
| PubMed reference number | 36678146 |
| e-ISSN | 20726643 |
| DOI | 10.3390/nu15020275 |
| Language | English |
| Publisher | MDPI |
| Publisher Date | 2023-01-05 |
| Access Restriction | Open |
| Rights License | Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). © 2023 by the authors. |
| Subject Keyword | pancreatic cancer sugar sweetened beverages artificially sweetened beverages diet lifestyle factors risk mortality |
| Content Type | Text |
| Resource Type | Article |
| Subject | Food Science Nutrition and Dietetics |
