Bactericide Activity of Cellulose Acetate/Silver Nanoparticles Asymmetric Membranes: Surfaces and Porous Structures Role.

Content Provider	Europe PMC
Author	Figueiredo, Ana Sofia Ferraria, Ana Maria Botelho do Rego, Ana Maria Monteiro, Silvia Santos, Ricardo Minhalma, Miguel Sánchez-Loredo, María Guadalupe Tovar-Tovar, Rosa Lina de Pinho, Maria Norberta
Editor	Gugliuzza, Annarosa
Copyright Year	2022
Abstract	The antibacterial properties of cellulose acetate/silver nanoparticles (AgNP) ultrafiltration membranes were correlated with their integral asymmetric porous structures, emphasizing the distinct features of each side of the membranes, that is, the active and porous layers surfaces. Composite membranes were prepared from casting solutions incorporating polyvinylpyrrolidone-covered AgNP using the phase inversion technique. The variation of the ratio acetone/formamide and the AgNP content resulted in a wide range of asymmetric porous structures with different hydraulic permeabilities. Comprehensive studies assessing the antibacterial activity against Escherichia coli (cell death and growth inhibition of bacteria in water) were performed on both membrane surfaces and in E. coli suspensions. The results were correlated with the surface chemical composition assessed by XPS. The silver-free membranes presented a generalized growth of E. coli, which is in contrast with the inhibition patterns displayed by the membranes containing AgNP. For the surface bactericide test, the growth inhibition depends on the accessibility of E. coli to the silver present in the membrane; as the XPS results show, the more permeable membranes (CA30 and CA34 series) have higher silver signal detected by XPS, which is correlated with a higher growth inhibition. On the other hand, the inhibition action is independent of the membrane porous structure when the membrane is deeply immersed in an E. coli inoculated suspension, presenting almost complete growth inhibition.
Volume Number	13
PubMed Central reference number	PMC9864199
Issue Number	1
PubMed reference number	36676811
Journal	Membranes (Basel)
e-ISSN	20770375
DOI	10.3390/membranes13010004
Language	English
Publisher	MDPI
Publisher Date	2022-12-21
Access Restriction	Open
Rights License	Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). © 2022 by the authors.
Subject Keyword	cellulose acetate/silver nanocomposite ultrafiltration membranes antimicrobial properties polyvinylpyrrolidone-coated silver nanoparticles surface characterization
Content Type	Text
Resource Type	Article
Subject	Chemical Engineering Process Chemistry and Technology Filtration and Separation