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Photothermal Sensitive 3D Printed Biodegradable Polyester Scaffolds with Polydopamine Coating for Bone Tissue Engineering.
| Content Provider | Europe PMC |
|---|---|
| Author | Huang, Zuoxun Li, Junfeng Chen, Xiaohu Yang, Qing Zeng, Xiyang Bai, Ruqing Wang, Li |
| Editor | Zhang, Hongbo Zhang, Wenjun (Chris) |
| Copyright Year | 2023 |
| Abstract | Biodegradable scaffolds with photothermal effects and customizable pore structures are a hot topic of research in the field of bone repair. In this study, we prepared porous scaffolds using poly(lactic acid) (PLA) as the raw material and customized the pore structure with 3D printing technology. First, we investigated the effect of pore structure on the mechanical properties of this 3D PLA scaffold. Subsequently, the optimally designed PLA scaffolds were coated with PDA to enhance their hydrophilicity and bioactivity. XRD (X-ray diffraction), FTIR (Fourier transform infrared spectroscopy) and EDS (Energy dispersive spectroscopy) results indicated that PDA was successfully coated on the surface of PLA scaffolds. SEM (Scanning electron microscopy) micrographs showed that the surface of the PDA/PLA scaffolds became rough. WCA (water contact angle) confirmed that the material has enhanced hydrophilic properties. PDA/PLA scaffolds exhibit a tunable photothermal effect under NIR (near infrared) irradiation. The 3D-printed PLA/PDA scaffolds have remarkable potential as an alternative material for repairing bone defects. |
| Journal | Polymers |
| Volume Number | 15 |
| PubMed Central reference number | PMC9861029 |
| Issue Number | 2 |
| PubMed reference number | 36679260 |
| e-ISSN | 20734360 |
| DOI | 10.3390/polym15020381 |
| Language | English |
| Publisher | MDPI |
| Publisher Date | 2023-01-11 |
| Access Restriction | Open |
| Rights License | Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). © 2023 by the authors. |
| Subject Keyword | 3D printing polylactic acid tissue engineering photothermal polydopamine coating |
| Content Type | Text |
| Resource Type | Article |
| Subject | Chemistry Polymers and Plastics |
