NDLI: Colorimetric Chemosensor Based on Fe<sub>3</sub>O<sub>4</sub> Magnetic Molecularly Imprinted Nanoparticles for Highly Selective and Sensitive Detection of Norfloxacin in Milk.

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Colorimetric Chemosensor Based on Fe₃O₄ Magnetic Molecularly Imprinted Nanoparticles for Highly Selective and Sensitive Detection of Norfloxacin in Milk.

Content Provider	Europe PMC
Author	Li, Maiquan Luo, Lingli Li, Jiayin Xiong, Yingzi Wang, Ling Liu, Xia
Editor	Noguer, Thierry
Copyright Year	2023
Abstract	Long-term use of norfloxacin (NOR) will cause NOR residues in foods and harm human bodies. The determination of NOR residues is important for guaranteeing food safety. In this study, a simple, selective, and label-free colorimetric chemosensor for in situ NOR detection was developed based on Fe3O4 magnetic molecularly imprinted nanoparticles (Fe3O4 MMIP NPs). The Fe3O4 MMIP NPs showed good peroxidase-like catalytic activity to 3,3′,5,5′-tetramethylbenzidine (TMB) and selective adsorption ability to NOR. The colorimetric chemosensor was constructed based on the Fe3O4 MMIP NPs-H2O2-TMB reaction system. The absorbance differences were proportional to the concentrations of NOR in the range of 10–300 ng/mL with a limit of detection at 9 ng/mL. The colorimetric chemosensor was successfully applied to detect NOR residue in milk. The recovery range was 78.2–95.81%, with a relative standard deviation of 2.1–9.88%. Together, the proposed colorimetric chemosensor provides a reliable strategy for the detection of NOR residues in foods.
Journal	Foods (Basel, Switzerland)
Volume Number	12
PubMed Central reference number	PMC9858306
Issue Number	2
PubMed reference number	36673377
e-ISSN	23048158
DOI	10.3390/foods12020285
Language	English
Publisher	MDPI
Publisher Date	2023-01-07
Access Restriction	Open
Rights License	Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). © 2023 by the authors.
Subject Keyword	Fe3O4 MMIP NPs peroxidase-like catalytic activity colorimetric chemosensor norfloxacin detection
Content Type	Text
Resource Type	Article
Subject	Microbiology Health (social science) Health Professions Food Science Plant Science

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Colorimetric Chemosensor Based on Fe3O4 Magnetic Molecularly Imprinted Nanoparticles for Highly Selective and Sensitive Detection of Norfloxacin in Milk.

Colorimetric Chemosensor Based on Fe₃O₄ Magnetic Molecularly Imprinted Nanoparticles for Highly Selective and Sensitive Detection of Norfloxacin in Milk.