NDLI: Curative Effects of Copper Iodide Embedded on Gallic Acid Incorporated in a Poly(vinyl alcohol) (PVA) Liquid Bandage.

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Curative Effects of Copper Iodide Embedded on Gallic Acid Incorporated in a Poly(vinyl alcohol) (PVA) Liquid Bandage.

Content Provider	Europe PMC
Author	Phetcharat, Putita Sangsanoh, Pakakrong Choipang, Chasuda Chaiarwut, Sonthaya Suwantong, Orawan Chuysinuan, Piyachat Supaphol, Pitt
Editor	Dasan, Arish Chandrasekar, Ashokraja Kohli, Nupur
Copyright Year	2023
Abstract	In daily life, people are often receiving minor cuts due to carelessness, leaving wounds on the skin. If wound healing is interrupted and the healing process does not finish, pathogens can easily enter wounds and cause infection. Liquid bandages are a fast and convenient way to help stop the bleeding of superficial wounds. Moreover, antibacterial agents in liquid bandages can promote wound restoration and fight bacteria. Herein, a poly(vinyl alcohol) (PVA) liquid bandage incorporating copper iodide nanoparticles (CuI NPs) was developed. CuI NPs were synthesized through green synthesis using gallic acid (GA) as a reducing and capping agent. The sizes of the CuI NPs, which were dependent on the concentration of GA, were 41.45, 43.51 and 49.71 nm, with the concentrations of gallic acid being 0, 2.5 mM and 5.0 mM, respectively. CuI NPs were analyzed using FTIR, XRD and SEM and tested for peroxidase-like properties and antibacterial activity. Then, PVA liquid bandages were formulated with different concentrations of stock CuI suspension. The results revealed that PVA liquid bandages incorporating 0.190% CuI synthesized with 5.0 mM of GA can kill bacteria within 24 h and have no harmful effects on human fibroblast cells.
Journal	Gels
Volume Number	9
PubMed Central reference number	PMC9857981
Issue Number	1
PubMed reference number	36661819
e-ISSN	23102861
DOI	10.3390/gels9010053
Language	English
Publisher	MDPI
Publisher Date	2023-01-08
Access Restriction	Open
Rights License	Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). © 2023 by the authors.
Subject Keyword	poly(vinyl alcohol) (PVA) cuprous iodide (CuI) green synthesis liquid bandage
Content Type	Text
Resource Type	Article
Subject	Bioengineering Biomaterials Polymers and Plastics Organic Chemistry

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