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A Rare Case of Thymic Rosai-Dorfman Disease Mimicking Malignancy on 18F-FDG PET/CT.
| Content Provider | Europe PMC |
|---|---|
| Author | Jia, Tongtong Zhang, Bin Zhang, Xiaoyi Xu, Xin Sang, Shibiao Deng, Shengming |
| Editor | Werner, Rudolf A. Rowe, Steven P. Solnes, Lilja B. |
| Copyright Year | 2022 |
| Abstract | Background Rosai-Dorfman disease (RDD), the massive lymphadenopathy characterized by the proliferation of sinus histiocytosis, is a relatively idiopathic benign disease with unknown etiology. We reported a rare case of thymic RDD detected by 18F-FDG PET/CT. A 23-year-old man with right-sided chest pain underwent 18F-FDG PET/CT scan, showing increased 18F-FDG uptake in an anterior mediastinal mass corresponding to a thymic lesion at an enhanced CT scan. The patient was referred to surgery with the clinical suspicion of thymic malignancy. The histological examination and immunohistochemical results confirmed RDD. Conclusions This was the first case report of RDD isolated to the thymus and initially presented with chest pain. Moreover, there was no characteristic painless neck lymphadenopathy at any stage of the disease course. Thus, for young patients with thymus mass, RDD should be considered a rare but possible diagnosis. |
| Related Links | https://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC9788635&blobtype=pdf |
| ISSN | 23791381 |
| Journal | Tomography |
| Volume Number | 8 |
| DOI | 10.3390/tomography8060237 |
| PubMed Central reference number | PMC9788635 |
| Issue Number | 6 |
| PubMed reference number | 36548529 |
| e-ISSN | 2379139X |
| Language | English |
| Publisher | MDPI |
| Publisher Date | 2022-11-28 |
| Access Restriction | Open |
| Rights License | Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). © 2022 by the authors. |
| Subject Keyword | Rosai-Dorfman disease sinus histiocytosis with massive lymphadenopathy histiocytosis 18F-FDG PET/CT |
| Content Type | Text |
| Resource Type | Article |
| Subject | Radiology, Nuclear Medicine and Imaging |