A Mini Review on Osteoporosis: From Biology to Pharmacological Management of Bone Loss.

Content Provider	Europe PMC
Author	Chin, Kok-Yong Ng, Ben Nett Rostam, Muhd Khairik Imran Muhammad Fadzil, Nur Farah Dhaniyah Raman, Vaishnavi Mohamed Yunus, Farzana Syed Hashim, Syed Alhafiz Ekeuku, Sophia Ogechi
Editor	Malaise, Olivier
Copyright Year	2022
Abstract	Osteoporosis refers to excessive bone loss as reflected by the deterioration of bone mass and microarchitecture, which compromises bone strength. It is a complex multifactorial endocrine disease. Its pathogenesis relies on the presence of several endogenous and exogenous risk factors, which skew the physiological bone remodelling to a more catabolic process that results in net bone loss. This review aims to provide an overview of osteoporosis from its biology, epidemiology and clinical aspects (detection and pharmacological management). The review will serve as an updated reference for readers to understand the basics of osteoporosis and take action to prevent and manage this disease.
Journal	Journal of Clinical Medicine [J Clin Med]
Volume Number	11
DOI	10.3390/jcm11216434
PubMed Central reference number	PMC9657533
Issue Number	21
PubMed reference number	36362662
e-ISSN	20770383
Language	English
Publisher	Molecular Diversity Preservation International (MDPI)
Publisher Date	2022-10-30
Access Restriction	Open
Subject Keyword	bone menopause osteoblast osteoclast osteocyte skeleton
Content Type	Text
Resource Type	Article
Subject	Medicine