Gender differences in Anxious-depressive symptomatology, Metabolic Syndrome and Colorectal Adenomas among outpatients undergoing colonoscopy: a cross-sectional study according to a PNEI perspective.

Content Provider	Europe PMC
Author	Rioli, Giulia Mattei, Giorgio Bonamici, Caterina Mancini, Stefano Alboni, Silvia Cannazza, Giuseppe Sena, Paola Roncucci, Luca Pingani, Luca Ferrari, Silvia Galeazzi, Gian Maria
Copyright Year	2022
Abstract	Background and aim of the work:To explore gender differences in patients suffering from anxious-depressive symptoms, Metabolic Syndrome (MetS) and Colorectal Adenomas (CRAs) in a sample of outpatients undergoing colonoscopy for screening purposes.Methods:Cross-sectional study. 126 consecutive outpatients of both sexes undergoing colonoscopy for non-specific abdominal symptoms between January 2015 and June 2021 at the Modena Policlinico General Hospital (Modena, Northern Italy) were enrolled. MetS was diagnosed according to ATPIII and IDF criteria. Anxiety and depression were assessed with the Hospital Anxiety and Depression Scale (HADS), while the Temperament and Character Inventory (TCI) was used to study personality. The SF-36 was also included as a measure of quality of life perception.Results:Among 126 outpatients (51.60% male) undergoing colonoscopy, 51 (44%) had CRAs, 54 (47%) MetS, 41 (41.40%) anxiety symptoms, 22 (22.20%) depressive symptoms and 13 (13.10%) combined anxious-depressive symptoms. HADS-Anxiety (t=2.68, p=0.01) and TCI Reward Dependence (TCI-RD) (t=3.01, p=0.00) mean scores were significantly higher in women; conversely, SF-36 Mental Component Summary scores were higher in men. CRAs were significantly prevalent in men (χ2=9.32, p=0.00) and were statistically significantly associated with male sex at the univariate logistic regression analysis (OR=3.27; p<0.01). At the multivariate logistic regression, diastolic hypertension (p<0.01) was positively associated with male sex, while TCI-RD (p=0.04) and HDL hypocholesterolemia (p=0.02) were inversely associated with male sex.Conclusions:Several significant gender differences in anxious-depressive symptoms, MetS and CRAs were found. These preliminary data suggest the need to consider gender specificities while implementing therapeutic, diagnostic, and preventive strategies. (www.actabiomedica.it)
ISSN	03924203
Journal	Acta Bio Medica : Atenei Parmensis
Volume Number	93
PubMed Central reference number	PMC9534235
Issue Number	4
PubMed reference number	36043977
e-ISSN	25316745
DOI	10.23750/abm.v93i4.12463
Language	English
Publisher	Mattioli 1885
Publisher Date	2022-08-31
Publisher Place	Italy
Access Restriction	Open
Rights License	This work is licensed under a Creative Commons Attribution 4.0 International License Copyright: © 2022 ACTA BIO MEDICA SOCIETY OF MEDICINE AND NATURAL SCIENCES OF PARMA
Subject Keyword	anxiety depression metabolic syndrome comorbidity outpatients
Content Type	Text
Resource Type	Article
Subject	Medicine