To have or not to have: expression of amino acid transporters during pathogen infection.

Content Provider	Europe PMC
Author	Tünnermann, Laura Colou, Justine Näsholm, Torgny Gratz, Regina
Abstract	The interaction between plants and plant pathogens can have significant effects on ecosystem performance. For their growth and development, both bionts rely on amino acids. While amino acids are key transport forms of nitrogen and can be directly absorbed from the soil through specific root amino acid transporters, various pathogenic microbes can invade plant tissues to feed on different plant amino acid pools. In parallel, plants may initiate an immune response program to restrict this invasion, employing various amino acid transporters to modify the amino acid pool at the site of pathogen attack. The interaction between pathogens and plants is sophisticated and responses are dynamic. Both avail themselves of multiple tools to increase their chance of survival. In this review, we highlight the role of amino acid transporters during pathogen infection. Having control over the expression of those transporters can be decisive for the fate of both bionts but the underlying mechanism that regulates the expression of amino acid transporters is not understood to date. We provide an overview of the regulation of a variety of amino acid transporters, depending on interaction with biotrophic, hemibiotrophic or necrotrophic pathogens. In addition, we aim to highlight the interplay of different physiological processes on amino acid transporter regulation during pathogen attack and chose the LYSINE HISTIDINE TRANSPORTER1 (LHT1) as an example.Supplementary InformationThe online version contains supplementary material available at 10.1007/s11103-022-01244-1.
Related Links	https://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC9213295&blobtype=pdf
ISSN	01674412
Journal	Plant Molecular Biology [Plant Mol Biol]
Volume Number	109
DOI	10.1007/s11103-022-01244-1
PubMed Central reference number	PMC9213295
Issue Number	4-5
PubMed reference number	35103913
e-ISSN	15735028
Language	English
Publisher	Springer Netherlands
Publisher Date	2022-02-01
Publisher Place	Dordrecht
Access Restriction	Open
Rights License	Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. © The Author(s) 2022
Subject Keyword	Amino acids Amino acid transporter Lysine histidine transporter (LHT) Organic nitrogen Pathogen defense Ethylene signaling
Content Type	Text
Resource Type	Article
Subject	Genetics Plant Science Medicine Agronomy and Crop Science