Loading...
Please wait, while we are loading the content...
Similar Documents
The association of pre-pregnancy BMI on leptin, ghrelin, adiponectin and insulin-like growth factor-1 in breast milk: a case-control study.
| Content Provider | Europe PMC |
|---|---|
| Author | Tekin Guler, Tugce Koc, Nevra Kara Uzun, Aysun Fisunoglu, Mehmet |
| Copyright Year | 2021 |
| Abstract | The nutrient composition of breast milk alters during lactation, and maternal BMI adds more intricacy into its complexity. We aimed to compare leptin, ghrelin, adiponectin and insulin-like growth factor-1 (IGF-1) levels of pre-feed and post-feed breast milk in mothers with obesity and normal weight, and tried to determine their effects on infants’ growth over weight for length z-score. Twenty obese and twenty normal weight mothers with 2-month-old infants were enrolled in this case–control study. Five millilitre pre-feed breast milk and 5 ml post-feed breast milk were collected. Breast milk leptin, ghrelin, adiponectin and IGF-1 were measured by commercial kits. The pre-feed breast milk of mothers with obesity had significantly higher levels of ghrelin than mothers with normal weight (P = 0·025), whereas the post-feed breast milk of mothers with normal weight had higher levels of adiponectin than the mothers with obesity (P = 0·010). No significant differences were observed in leptin and IGF-1 levels between the two groups. Post-feed breast milk IGF-1 levels of mothers with obesity were correlated with infant’s weight for length z-score at 2 months (r −0·476; P = 0·034). In linear regression models, parity affected the ghrelin in pre-feed breast milk (P = 0·025). Our results revealed that maternal pre-pregnancy BMI was associated with breast milk components. |
| Related Links | https://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC9201832&blobtype=pdf |
| Page Count | 7 |
| ISSN | 00071145 |
| Journal | The British Journal of Nutrition [Br J Nutr] |
| Volume Number | 127 |
| PubMed Central reference number | PMC9201832 |
| Issue Number | 11 |
| PubMed reference number | 34348809 |
| e-ISSN | 14752662 |
| DOI | 10.1017/s0007114521002932 |
| Language | English |
| Publisher | Cambridge University Press |
| Publisher Date | 2021-08-05 |
| Publisher Place | Cambridge, UK |
| Access Restriction | Open |
| Rights License | This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited. © The Author(s) 2021 |
| Subject Keyword | Breast milk Pre-pregnancy BMI Appetite hormones Pre-feed breast milk Post-feed breast milk |
| Content Type | Text |
| Resource Type | Article |
| Subject | Nutrition and Dietetics Medicine |
