NDLI: Paroxysmal Sympathetic Hyperactivity After Traumatic Brain Injury: What Is Important to Know?

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Paroxysmal Sympathetic Hyperactivity After Traumatic Brain Injury: What Is Important to Know?

Content Provider	Europe PMC
Author	Louraoui, Sidi Mamoun Fliyou, Fadwa Aasfara, Jehanne El Azhari, Abdessamad
Editor	Muacevic, Alexander Adler, John R
Copyright Year	2022
Abstract	Traumatic brain injury (TBI) is one of the leading causes of morbidity and mortality. The etiologies of TBI are varied and its complications can lead to paroxysmal sympathetic hyperactivity that was first described as a "sympathetic storm" or "diencephalic autonomic seizure." The clinical manifestations are rapid and sudden onset of sympathetic hyperactivity characterized by tachycardia, systolic hypertension, hyperthermia, tachypnea, and diaphoresis, all summarized in the latest and most accepted diagnostic criteria. The pathophysiology remains controversial with many theories proposed. Given the clinical manifestations, the complications, outcomes, and lack of popularity of the syndrome, we report a case treated in our institution and review the current pathophysiology and treatment options.
Journal	Cureus
Volume Number	14
DOI	10.7759/cureus.24693
PubMed Central reference number	PMC9161703
Issue Number	5
PubMed reference number	35663695
e-ISSN	21688184
Language	English
Publisher	Cureus
Publisher Date	2022-05-03
Publisher Place	Palo Alto (CA)
Access Restriction	Open
Subject Keyword	psh dysautonomia sympathetic storm traumatic brain injury paroxysmal sympathetic hyperactivity
Content Type	Text
Resource Type	Case study
Subject	Medicine

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