Nomogram to Predict the Risk of Postoperative Anxiety and Depression in Colorectal Cancer Patients.

Content Provider	Europe PMC
Author	Hu, Zhiqiao Zhang, Hao Wang, Jiaqi Xiong, Huan Liu, Yunxiao Zhu, Yihao Chang, Zewen Hu, Hanqing Tang, Qingchao
Copyright Year	2022
Abstract	PurposeTo develop and validate the risk nomogram to predict the likelihood of postoperative anxiety and depression in colorectal cancer (CRC) patients.MethodsA total of 602 CRC patients from the Second Affiliated Hospital of Harbin Medical University were included in the study and divided into development set and validation set with the 2:1 ratio randomly. Logistic regression model was used to determine independent factors contributing to postoperative anxiety and depression, which were subsequently applied to build the nomogram for predicting postoperative anxiety and depression. The performance of the risk nomogram was appraised by the area under the receiver operating curve (AUC), calibration curves and decision curve analyses (DCA).ResultsGender, personal status, income, adjuvant therapy, the Eastern Cooperative Oncology Group Scale (ECOG) score, comorbidity, postoperative complications and stoma status were significant indicators for postoperative anxiety and depression. The AUCs for the development and validation sets were 0.792 and 0.812 for the postoperative anxiety nomogram and 0.805 and 0.825 for the postoperative depression nomogram. Additionally, calibration curves and decision curve analyses also determined the reliable clinical importance of the proposed nomogram.ConclusionThe current study constructed the risk nomogram for postoperative anxiety and depression and could help clinicians determine high-risk patients to some extent.
Page Count	15
Volume Number	15
PubMed Central reference number	PMC9109807
PubMed reference number	35585997
Journal	International Journal of General Medicine [Int J Gen Med]
e-ISSN	11787074
DOI	10.2147/IJGM.S350092
Language	English
Publisher	Dove
Publisher Date	2022-05-12
Access Restriction	Open
Rights License	This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php). © 2022 Hu et al.
Subject Keyword	nomogram colorectal cancer postoperative anxiety and depression
Content Type	Text
Resource Type	Article
Subject	Medicine