Quality of life of colorectal cancer survivors participating in a pilot randomized controlled trial of physical activity trackers and daily text messages.

Content Provider	Europe PMC
Author	Chan, Hilary Van Loon, Katherine Kenfield, Stacey A. Chan, June M. Mitchell, Emily Zhang, Li Paciorek, Alan Joseph, Galen Laffan, Angela Atreya, Chloe Fukuoka, Yoshimi Miaskowski, Christine Meyerhardt, Jeffrey A. Venook, Alan P. Van Blarigan, Erin L.
Abstract	PurposeThere are over 1.3 million colorectal cancer (CRC) survivors in the USA, many of whom report lower health-related quality of life (HRQoL) years after treatment. This study aimed to explore the effect of digital health tools on HRQoL in CRC survivors.MethodsWe conducted a two-arm, randomized controlled trial of 42 subjects who had completed treatment for CRC. Participants in the intervention arm received a Fitbit Flex™ and daily text messages for 12 weeks. HRQoL was assessed as a secondary endpoint in both arms at enrollment and 12 weeks using the Medical Outcomes Study Short Form Survey (SF-36) and the Functional Assessment of Cancer Therapy–Colorectal (FACT-C). Survey score changes from enrollment to 12 weeks were compared between the two arms using independent t tests, and scores at enrollment and 12 weeks were compared using paired t tests.ResultsAn increase in the FACT-C functional well-being subscale was observed in individuals in the intervention arm pre- to post-intervention (median difference, 2; interquartile range (IQR), 1, 4; P = .02). Although the between-group comparison was not statistically significant, no change in the functional well-being subscale was observed in the control arm (median difference, 0; IQR, 1, 1; P = .71). No other measures of HRQoL appeared to differ within arm across time points or between arms.ConclusionA 12-week digital physical activity intervention may improve functional well-being among CRC survivors. Larger randomized studies are needed to determine if digital health tools improve functional well-being among CRC survivors and if this improvement can be sustained over time.Trial registrationNCT02966054; registration date, November 17, 2016Supplementary InformationThe online version contains supplementary material available at 10.1007/s00520-022-06870-5.
ISSN	09414355
Journal	Supportive Care in Cancer
Volume Number	30
PubMed Central reference number	PMC8942969
Issue Number	5
PubMed reference number	35119520
e-ISSN	14337339
DOI	10.1007/s00520-022-06870-5
Language	English
Publisher	Springer Berlin Heidelberg
Publisher Date	2022-02-04
Publisher Place	Berlin/Heidelberg
Access Restriction	Open
Rights License	Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. © The Author(s) 2022
Subject Keyword	Colorectal cancer Quality of life
Content Type	Text
Resource Type	Article
Subject	Rehabilitation Oncology (nursing) Oncology