Disseminated Histoplasmosis Presenting as Acute Respiratory Distress Syndrome and Disseminated Intravascular Coagulation in an HIV Positive Immigrant from Central America.

Content Provider	Europe PMC
Author	Pata, Ramakanth Nway, Nway Lutaya, Innocent Chen, Victor
Editor	Muacevic, Alexander Adler, John R
Copyright Year	2022
Abstract	Histoplasmosis rarely causes significant illness in immunocompetent patients. In endemic areas such as the Midwestern United States and Central America, most people are infected, but are rarely symptomatic, with variable presentation. The illness is usually self-limited in immunocompetent individuals. However, in immunocompromised patients, Histoplasma capsulatum can disseminate to various organs and should be suspected especially in the endemic areas or if there is a significant travel history involving these areas. We present a case of a 65-year-old male originally from Central America with no known past medical history presenting with Acute Respiratory Distress Syndrome complicated by disseminated intravascular coagulation due to acute histoplasmosis and incidentally found to have HIV/AIDS.
Journal	Cureus
Volume Number	14
DOI	10.7759/cureus.21942
PubMed Central reference number	PMC8901384
Issue Number	2
PubMed reference number	35273883
e-ISSN	21688184
Language	English
Publisher	Cureus
Publisher Date	2022-02-05
Publisher Place	Palo Alto (CA)
Access Restriction	Open
Subject Keyword	histoplasma immigrant hiv dic ards histoplasma capsulatum disseminated histoplasmosis
Content Type	Text
Resource Type	Case study
Subject	Medicine