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Alopecia in patients with COVID-19: A systematic review and meta-analysis.
| Content Provider | Europe PMC |
|---|---|
| Author | Nguyen, Betty Tosti, Antonella |
| Copyright Year | 2022 |
| Abstract | BackgroundCOVID-19 is associated with androgenetic alopecia (AGA), telogen effluvium (TE), and alopecia areata (AA). No studies have analyzed the aggregate data to date.ObjectiveWe conducted a systematic review to characterize the types, incidence, timing, and clinical outcomes of COVID-19–associated alopecia.MethodsWe searched PubMed/MEDLINE, Scopus, and Embase for articles published between November 2019 and August 2021 using the key words “alopecia” or “hair” and COVID-19–related search terms, identifying 41 original articles describing patients with alopecia and COVID-19.ResultsThe current review included 1826 patients with alopecia and COVID-19 (mean age, 54.5 years; 54.3% male). The most common types of alopecia identified were AGA (30.7%, 86.4% male), TE (19.8%, 19.3% male), and AA (7.8%, 40.0% male). AGA preceded COVID-19 symptoms. TE was usually newly triggered by COVID-19 (93.6%). AA usually occurred in patients with preexisting disease (95.1%).LimitationsDefinitions of COVID-19 onset varied. Studies differed in methodology and were susceptible to reporting and sampling bias. Studies with large sample sizes may exert a disproportionate influence on data.ConclusionAGA may be a risk factor for severe COVID-19, whereas TE presents as a sequela of COVID-19. AA generally occurs as a relapse in patients with preexisting alopecia. |
| Related Links | https://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC8860672&blobtype=pdf |
| Journal | JAAD International [JAAD Int] |
| Volume Number | 7 |
| DOI | 10.1016/j.jdin.2022.02.006 |
| PubMed Central reference number | PMC8860672 |
| PubMed reference number | 35224518 |
| e-ISSN | 26663287 |
| Language | English |
| Publisher | Elsevier |
| Publisher Date | 2022-02-22 |
| Access Restriction | Open |
| Rights License | This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). © 2022 by the American Academy of Dermatology, Inc. Published by Elsevier Inc. |
| Subject Keyword | alopecia areata alopecia anagen effluvium androgenetic alopecia coronavirus disease 2019 COVID-19 hair loss SARS-CoV-2 telogen effluvium AA, alopecia areata ADT, androgen-deprivation therapy AE, anagen effluvium AGA, androgenetic alopecia PA, pressure-induced alopecia TE, telogen effluvium |
| Content Type | Text |
| Resource Type | Article |
| Subject | Dermatology |
