Perceived HIV Stigma, Depressive Symptoms, Self-esteem, and Suicidal Ideation Among People Living with HIV/AIDS in China: a Moderated Mediation Modeling Analysis.

Content Provider	Europe PMC
Author	Wei, Liqing Yan, Hong Guo, Menglan Tian, Jiawei Jiang, Qingqing Zhai, Mengxi Zhu, Biao Yin, Xiaohong Liao, Yu Yu, Bin
Abstract	ObjectiveSuicidal ideation is an important public health challenge among people living with HIV (PLWH) across the world and in China. HIV stigma, depression, and self-esteem have been associated with suicidal ideation. However, the underlying mechanisms remain not fully understood.MethodsStudy data were derived from a sample of 465 PLWH in China. Suicidal ideation after HIV diagnosis was used as outcome variable. HIV stigma, depressive symptoms, and self-esteem were measured using reliable instruments and used as predictor, mediator, and moderator, respectively. Mediation and moderated mediation model were used for data analysis.Results31.6% of PLWH in China had suicidal ideation after HIV diagnosis. The association between perceived HIV stigma and suicidal ideation was partially mediated by depression (indirect effect = 0.02, 95% CI = [0.02, 0.03]) with the path from perceived HIV stigma to depressive symptoms being moderated by self-esteem (interaction effect =  − 0.02, 95% CI [− 0.03, − 0.01]).ConclusionsStudy findings suggested a mediation mechanism of HIV stigma on suicidal ideation through depressive symptoms, and self-esteem might weaken the mediation mechanism by moderating the perceived HIV stigma-depressive symptoms pathway.
Related Links	https://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC8853186&blobtype=pdf
ISSN	21973792
Journal	Journal of Racial and Ethnic Health Disparities [J Racial Ethn Health Disparities]
Volume Number	10
DOI	10.1007/s40615-022-01255-0
PubMed Central reference number	PMC8853186
Issue Number	2
PubMed reference number	35165837
e-ISSN	21968837
Language	English
Publisher	Springer International Publishing
Publisher Date	2022-02-14
Publisher Place	Gewerbestrasse 11, Cham, Ch 6330, Switzerland
Access Restriction	Open
Rights License	This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic. © W. Montague Cobb-NMA Health Institute 2022
Subject Keyword	People living with HIV Suicidal ideation Perceived HIV stigma Depressive symptoms Self-esteem Moderated mediation
Content Type	Text
Resource Type	Article
Subject	Sociology and Political Science Public Health, Environmental and Occupational Health Health (social science) Anthropology Health Policy