Population genetic analysis of 12 X-chromosomal STRs in a Swiss sample.

Content Provider	Europe PMC
Author	Bottinelli, Michel Gouy, Alexandre Utz, Silvia Zieger, Martin
Abstract	X-chromosomal STRs are a powerful tool to assess a broad variety of complex kinship scenarios. We introduce herewith the first Swiss X-STR dataset based on 1198 individuals (592 female, 606 male), characterized with the Qiagen Investigator® Argus X-12 QS multiplex kit. Anomalous allele patterns, allele and haplotype frequencies, and forensic and population genetic parameters are presented. We detected linkage disequilibrium within three out of the four designated linkage groups and no apparent intra-national population substructure. We compared the dataset to a global panel of X-STR datasets and it fits well in the European context, as expected.Supplementary informationThe online version contains supplementary material available at 10.1007/s00414-021-02684-y.
Related Links	https://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC8847170&blobtype=pdf
ISSN	09379827
Journal	International Journal of Legal Medicine [Int J Legal Med]
Volume Number	136
DOI	10.1007/s00414-021-02684-y
PubMed Central reference number	PMC8847170
Issue Number	2
PubMed reference number	34420081
e-ISSN	14371596
Language	English
Publisher	Springer Berlin Heidelberg
Publisher Date	2021-08-22
Publisher Place	Berlin/Heidelberg
Access Restriction	Open
Rights License	Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. © The Author(s) 2021
Subject Keyword	Switzerland X-STR Kinship Population data Forensics
Content Type	Text
Resource Type	Article
Subject	Pathology and Forensic Medicine