Case of Pulmonary Extramedullary Hematopoiesis Responding to Ruxolitinib.

Content Provider	Europe PMC
Author	Fujimoto, Ayumi Hamaguchi, Shunichi Suzuki, Ritsuro
Copyright Year	2022
Abstract	We report a case of 43-year-old woman diagnosed with essential thrombocythemia in 1992. She was diagnosed with secondary myelofibrosis in 2011. Later, she suffered mild dyspnea, which gradually worsened. She was admitted to our hospital to evaluate the cause in 2014. Chest computed tomography showed ground-glass opacity (GGO) in the lungs. A lung biopsy revealed various hematopoietic cells, including abnormal megakaryocytes, infiltrating the alveolar septum, suggesting pulmonary extramedullary hematopoiesis. She was successfully treated by ruxolitinib and her disease is well controlled for more than 7 years. To keep this phenomenon in mind when see the patients with dyspnea is important.
Related Links	https://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC8844769&blobtype=pdf
Journal	Leukemia Research Reports [Leuk Res Rep]
Volume Number	17
DOI	10.1016/j.lrr.2022.100290
PubMed Central reference number	PMC8844769
PubMed reference number	35198370
e-ISSN	22130489
Language	English
Publisher	Elsevier
Publisher Date	2022-02-07
Access Restriction	Open
Rights License	This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). © 2022 The Authors. Published by Elsevier Ltd.
Subject Keyword	Pulmonary Extramedullary Hematopoiesis Myelofibrosis Ruxolitinib Case report
Content Type	Text
Resource Type	Article
Subject	Hematology Oncology