Prolonged survival time with surgical therapy in different types of thymoma: an analysis based on Surveillance Epidemiology and End Results Database.

Content Provider	Europe PMC
Author	Li, Jinsong Liu, Quan Zheng, Zhikun Li, Shoukang
Copyright Year	2020
Abstract	BackgroundThymoma is the most common tumor within the anterior mediastinum though it is still a rare tumor disease. Surgery is considered to be one of the most important treatment methods for it, while radiotherapy and platinum-based chemotherapy are also in use. Based on the Surveillance, Epidemiology and End Results (SEER) database, we conducted our research and determined the value of operation in the treatment of thymoma.MethodsIn total, 1,587 patients with thymoma were selected out from the database. We grouped them according to type and stage of thymoma. We used cox-regression analysis to selected meaningful factors. Kaplan-Meier method was used for survival analysis.ResultsThe mean survival times of patients with type A, B, C thymoma were 130.79, 123.81, 77.18 months orderly. Among all 1,587 patients, the mean survival time of those treated with surgery was 124.92 months, while it was 65.03 months for those without surgery treatment (P<0.05). Within each group of patients with the same kind of and same stage thymoma, who got surgical treatment had a longer survival period (P<0.05).ConclusionsType c thymoma had the worst prognosis. Patients who received surgical treatment had longer survival time. And it didn’t matter what type or what stage of thymoma.
ISSN	2218676X
Journal	Translational Cancer Research
Volume Number	9
PubMed Central reference number	PMC8798356
Issue Number	10
PubMed reference number	35117202
e-ISSN	22196803
DOI	10.21037/tcr-20-951
Language	English
Publisher	AME Publishing Company
Publisher Date	2020-10-01
Access Restriction	Open
Rights License	Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0/. 2020 Translational Cancer Research. All rights reserved.
Subject Keyword	Thymoma surgery treatment survival time Surveillance, Epidemiology and End Results database (SEER database)
Content Type	Text
Resource Type	Article
Subject	Radiology, Nuclear Medicine and Imaging Cancer Research Oncology