Laparoscopic Kasai portoenterostomy can be a standard surgical procedure for treatment of biliary atresia.

Content Provider	Europe PMC
Author	Shirota, Chiyoe Hinoki, Akinari Tainaka, Takahisa Sumida, Wataru Kinoshita, Fumie Yokota, Kazuki Makita, Satoshi Amano, Hizuru Nakagawa, Yoichi Uchida, Hiroo
Copyright Year	2022
Abstract	BACKGROUNDBiliary atresia (BA) is a rare pediatric disease.AIMTo compare the outcomes of laparoscopic portoenterostomy (Lap-PE) with those of laparotomy (Open-PE) at a single institution. METHODSThe surgical outcomes of PE were retrospectively analyzed for patients with a non-correctable type of BA from 2003 to 2020.RESULTSThroughout the assessment period, 119 patients received PE for BA treatment, including 66 Open-PE and 53 Lap-PE cases. Although the operation duration was longer (medians: for Open-PE, 242 min; for Lap-PE, 341 min; P < 0.001), blood loss was considerably less (medians: for Open-PE, 52 mL; for Lap-PE, 24 mL; P < 0.001) in the Lap-PE group than in the Open-PE group. The postoperative recovery of the Lap-PE group was more favorable; specifically, both times to resume oral intake and drain removal were significantly shorter in the Lap-PE group. Complete resolution of jaundice was observed in 45 Open-PE cases and 42 Lap-PE cases, with no statistically significant difference (P = 0.176). Native liver survival rates were >80% for both groups for the first half year post surgery, followed by a gradual decrease with time; there were no statistically significant differences in the native liver survival rates for any durations assessed.CONCLUSIONLap-PE could be a standard therapy for BA.
Related Links	https://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC8790325&blobtype=pdf
Journal	World Journal of Gastrointestinal Surgery [World J Gastrointest Surg]
Volume Number	14
DOI	10.4240/wjgs.v14.i1.56
PubMed Central reference number	PMC8790325
Issue Number	1
PubMed reference number	35126863
e-ISSN	19489366
Language	English
Publisher	Baishideng Publishing Group Inc
Publisher Date	2022-01-01
Access Restriction	Open
Rights License	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
Subject Keyword	Laparoscopic Kasai portoenterostomy Biliary atresia Native liver survival Pediatric Liver Transplantation
Content Type	Text
Resource Type	Article
Subject	Gastroenterology