Microfluidic technology and its application in the point-of-care testing field.

Content Provider	Europe PMC
Author	Xie, Yaping Dai, Lizhong Yang, Yijia
Copyright Year	2022
Abstract	Since the outbreak of the coronavirus disease 2019 (COVID-19), countries around the world have suffered heavy losses of life and property. The global pandemic poses a challenge to the global public health system, and public health organizations around the world are actively looking for ways to quickly and efficiently screen for viruses. Point-of-care testing (POCT), as a fast, portable, and instant detection method, is of great significance in infectious disease detection, disease screening, pre-disease prevention, postoperative treatment, and other fields. Microfluidic technology is a comprehensive technology that involves various interdisciplinary disciplines. It is also known as a lab-on-a-chip (LOC), and can concentrate biological and chemical experiments in traditional laboratories on a chip of several square centimeters with high integration. Therefore, microfluidic devices have become the primary implementation platform of POCT technology. POCT devices based on microfluidic technology combine the advantages of both POCT and microfluids, and are expected to shine in the biomedical field. This review introduces microfluidic technology and its applications in combination with other technologies.
Related Links	https://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC8769924&blobtype=pdf
Journal	Biosensors & Bioelectronics [Biosens Bioelectron X]
Volume Number	10
DOI	10.1016/j.biosx.2022.100109
PubMed Central reference number	PMC8769924
PubMed reference number	35075447
e-ISSN	25901370
Language	English
Publisher	The Author(s). Published by Elsevier B.V.
Publisher Date	2022-01-20
Access Restriction	Open
Rights License	Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. © 2022 The Author(s)
Subject Keyword	Microfluidic technology Point-of-care testing (POCT) Biosensors Loop-mediated isothermal amplification (LAMP) Three-dimension (3D) printing
Content Type	Text
Resource Type	Article
Subject	Biophysics Biotechnology Electrochemistry Biomedical Engineering