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The Role of Medical Acupuncture Therapy in Alzheimer's Disease.
| Content Provider | Europe PMC |
|---|---|
| Author | Teja, Yolanda Helianthi, Dwi Rachma Nareswari, Irma |
| Copyright Year | 2021 |
| Description | Objective: Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by memory deficits and other cognitive disorders, which can be accompanied by personality changes. Long-term use of medications available to treat AD today have a variety of side-effects. Acupuncture, as a nonpharmacologic therapeutic modality providing stimulation at acupuncture points, using filiform needles, has been widely tested and used to manage of AD and can be a therapeutic option, considering its effectiveness and lack of side-effects. Methods: This literature review examines the role of acupuncture in AD treatment. Results: Acupuncture can ameliorate AD symptoms through decreasing amyloid-β protein, reducing neuroinflammation, enhancing the antioxidant system, improving neurogenesis, enhancing prosurvival protein, reducing proapoptotic protein, and regulating brain energy metabolism. Conclusions: According to various research findings, acupuncture may be a therapeutic choice for addressing AD that avoids the long-term side-effects caused by medical therapy. |
| Abstract | Objective: Alzheimer's disease (AD) is a progressiveneurodegenerative disorder characterized by memory deficits and other cognitivedisorders, which can be accompanied by personality changes. Long-term use ofmedications available to treat AD today have a variety of side-effects.Acupuncture, as a nonpharmacologic therapeutic modality providing stimulation atacupuncture points, using filiform needles, has been widely tested and used tomanage of AD and can be a therapeutic option, considering its effectiveness andlack of side-effects. Methods: This literature review examines the role of acupuncture inAD treatment. Results: Acupuncture can ameliorate AD symptoms through decreasingamyloid-β protein, reducing neuroinflammation, enhancing the antioxidantsystem, improving neurogenesis, enhancing prosurvival protein, reducingproapoptotic protein, and regulating brain energy metabolism. Conclusions: According to various research findings, acupuncture maybe a therapeutic choice for addressing AD that avoids the long-term side-effectscaused by medical therapy. |
| Related Links | https://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC8717884&blobtype=pdf |
| Page Count | 7 |
| ISSN | 19336586 |
| Volume Number | 33 |
| DOI | 10.1089/acu.2021.0014 |
| PubMed Central reference number | PMC8717884 |
| Issue Number | 6 |
| PubMed reference number | 34987697 |
| Journal | Medical Acupuncture [Med Acupunct] |
| e-ISSN | 19336594 |
| Language | English |
| Publisher | Mary Ann Liebert, Inc., publishers |
| Publisher Date | 2021-12-16 |
| Publisher Place | USA |
| Access Restriction | Open |
| Rights License | Copyright 2021, Mary Ann Liebert, Inc.,publishers |
| Subject Keyword | Alzheimer's disease acupuncture amyloid-β (Aβ) plaques neurofibrillary tangles τ-protein |
| Content Type | Text |
| Resource Type | Article |
| Subject | Complementary and Alternative Medicine |
