NDLI: Reversible severe tricuspid regurgitation associated with Graves' disease: A case report.

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Reversible severe tricuspid regurgitation associated with Graves' disease: A case report.

Content Provider	Europe PMC
Author	Lee, Ja-Yeon Lee, Sun Hwa Kim, Won Ho
Editor	Saranathan., Maya
Copyright Year	2021
Abstract	AbstractRationale:Graves’ disease is the most common cause of thyrotoxicosis. Cardiovascular signs and symptoms are frequent in patients with thyrotoxicosis and right heart failure with severe tricuspid regurgitation (TR) is a rare manifestation of hyperthyroidism.Patient concerns:A 41-year-old woman with a history of Graves’ disease presented to the emergency department with worsening generalized edema and dyspnea for a month.Diagnosis:The laboratory test results revealed suppressed thyroid-stimulating hormone (TSH), elevated levels of free thyroxine and anti-TSH receptor antibody, and negative anti-thyroid peroxidase and anti-thyroglobulin antibodies. Transthoracic echocardiography showed severe TR associated with incomplete coaptation of tricuspid valve due to dilated right ventricle (RV), moderate resting pulmonary hypertension, and preserved biventricular systolic function.Interventions and outcomes:After 6 months of antithyroid treatment, her thyroid function was restored euthyroid state and she was fully recovered from right heart failure. Follow-up echocardiography showed complete disappearance of severe TR and pulmonary hypertension and normalization of RV dimension.Lessons:Severe TR can be rarely associated with thyrotoxicosis, but this is reversible and can be completely recovered with normalization of thyroid function.
ISSN	00257974
Journal	Medicine
Volume Number	100
PubMed Central reference number	PMC8702235
Issue Number	51
PubMed reference number	34941195
e-ISSN	15365964
DOI	10.1097/md.0000000000028432
Language	English
Publisher	Lippincott Williams & Wilkins
Publisher Date	2021-12-01
Publisher Place	Hagerstown, MD
Access Restriction	Open
Rights License	This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. http://creativecommons.org/licenses/by/4.0 Copyright © 2021 the Author(s). Published by Wolters Kluwer Health, Inc.
Subject Keyword	Graves’ disease heart failure tricuspid regurgitation
Content Type	Text
Resource Type	Article
Subject	Medicine

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