Localized gastric amyloidosis successfully treated with endoscopic submucosal dissection: A case report.

Content Provider	Europe PMC
Author	Oh, Gyu Man Park, Seun Ja Kim, Jae Hyun Jung, Kyoungwon Kim, Sung Eun Moon, Won Park, Moo In Chang, Hee-Kyung
Editor	Saranathan., Maya
Copyright Year	2021
Abstract	AbstractRationale:Amyloidosis is a general term that refers to the extracellular deposition of amyloid. The amyloid can also be deposited in a single organ. However, cases of localized gastric amyloidosis have rarely been reported. Here, we report a case of localized gastric amyloidosis that was successfully treated with endoscopic submucosal dissection.Patient concern:A 60-years-old man underwent esophagogastroduodenoscopy as part of a regular check-up without any comorbidities or symptoms.Diagnostics:A 12 mm-sized, round, elevated lesion with a central depression, which was covered with normal mucosa, and located on the greater curvature of the lower body of the stomach was discovered during endoscopy. Subsequently, endoscopic ultrasonography was performed, which revealed a 11.7 mm-sized, hypoechoic, heterogeneous lesion located in the muscularis mucosa and submucosa. A biopsy was performed, and amyloid deposition was confirmed. Although other investigations for checking systemic amyloidosis were performed, there were no specific findings. Therefore, the final diagnosis was localized gastric amyloidosis.Interventions:Endoscopic submucosal dissection was performed according to the patient's request and the lesion was completely removed.Outcomes:The patient was followed-up for 3 years without any recurrence.Conclusions:Endoscopic submucosal dissection can be good diagnostic and treatment option for localized gastric amyloidosis.
ISSN	00257974
Journal	Medicine
Volume Number	100
PubMed Central reference number	PMC8702132
Issue Number	51
PubMed reference number	34941190
e-ISSN	15365964
DOI	10.1097/md.0000000000028422
Language	English
Publisher	Lippincott Williams & Wilkins
Publisher Date	2021-12-01
Publisher Place	Hagerstown, MD
Access Restriction	Open
Rights License	This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. http://creativecommons.org/licenses/by/4.0 Copyright © 2021 the Author(s). Published by Wolters Kluwer Health, Inc.
Subject Keyword	amyloidosis case report endoscopic submucosal dissection endoscopic ultrasonography
Content Type	Text
Resource Type	Article
Subject	Medicine