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Inactivating Gene Expression with Antisense Modified Oligonucleotides.
| Content Provider | Europe PMC |
|---|---|
| Author | Altman, Sidney Angele-Martinez, Carlos |
| Copyright Year | 2021 |
| Abstract | Modified nucleotides, including phosphoramidates and mesyl nucleotides, arevery effective in inactivating gene expression in bacteria. Gyr Ais the target gene in several organisms, including Plasmodiumfalciparum. Antisense reactions with bacteria infecting citrus plantsare promising but incomplete. Human tissue culture cells assayed with adifferent target are also susceptible to the presence of mesyl oligonucleotides. |
| Related Links | https://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC8526185&blobtype=pdf |
| ISSN | 20758251 |
| Journal | Acta Naturae |
| Volume Number | 13 |
| DOI | 10.32607/actanaturae.11522 |
| PubMed Central reference number | PMC8526185 |
| Issue Number | 3 |
| PubMed reference number | 34707901 |
| Language | English |
| Publisher | A.I. Gordeyev |
| Publisher Date | 2021-07-01 |
| Access Restriction | Open |
| Rights License | This is an open-access article distributed under the terms of theCreative Commons Attribution License, which permits unrestricted use,distribution, and reproduction in any medium, provided the original work isproperly cited. Copyright ® 2021 National Research University Higher School of Economics. |
| Subject Keyword | modified nucleotides gene expression bacteria Plasmodium falciparum citrus plants |
| Content Type | Text |
| Resource Type | Article |
| Subject | Molecular Biology Biochemistry Molecular Medicine Biotechnology |