Incidence and predictors of permanent pacemaker implantation after surgical aortic v alve replacement: Data of the Netherlands Heart Registration (NHR).

Content Provider	Europe PMC
Author	Ravaux, Justine M. Van Kuijk, Sander MJ Di Mauro, Michele Vernooy, Kevin Bidar, Elham Mariani, Silvia Dato, Giulia Actis Van′t Hof, Arnoud W Veenstra, Leo Kats, Suzanne Houterman, Saskia Maessen, Jos G Lorusso, Roberto
Abstract	AbstractObjectivePermanent pacemaker implantation (PPI) after surgical aortic valve replacement (SAVR) remains a frequent complication. Predictors, however, have been mainly investigated in single‐center studies. Therefore, nationwide data were used to identify patients—and procedural risk factors for postoperative PPI.Materials and MethodsData were retrospectively collected from the Netherlands Heart Registration (NHR). Patients enrolled in the NHR undergoing isolated SAVR from 2013 to 2019 were analyzed. Primary endpoint was in‐hospital PPI during hospitalization after SAVR.ResultsFrom the NHR database, 5600 patients with symptomatic aortic valve stenosis were included in the study. Crude incidence of post‐SAVR PPI was 4.0%. Backward regression analysis identified previous cardiac surgery (odds ratio [OR]: 1.80; 95% confidence interval [CI]: 1.18–2.76), extra‐corporeal circulation time (OR: 1.01; 95% CI: 1.00–1.01), vasopressor use (OR: 2.66; 95% CI: 1.79–3.96) and in‐hospital cardiac conduction abnormalities (OR: 4.48; 95% CI: 3.36–5.98) as potential predictors for PPI. Across the time, PPI after SAVR significantly increased (OR: 1.11; 95% CI: 1.03–1.21).ConclusionsFrom this nationwide analysis, PPI after SAVR remains a low but increasingly frequent complication. Several predictive factors for postoperative PPI after SAVR have been identified and might be useful for patient informed consent about potential adverse event rate.
Related Links	https://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC8518121&blobtype=pdf
Page Count	9
ISSN	08860440
Journal	Journal of Cardiac Surgery [J Card Surg]
Volume Number	36
DOI	10.1111/jocs.15803
PubMed Central reference number	PMC8518121
Issue Number	10
PubMed reference number	34250647
e-ISSN	15408191
Language	English
Publisher	John Wiley and Sons Inc.
Publisher Date	2021-07-11
Publisher Place	Hoboken
Access Restriction	Open
Rights License	This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made. © 2021 The Authors. Journal of Cardiac Surgery Published by Wiley Periodicals LLC
Subject Keyword	aortic stenosis permanent pacemaker implantation surgical aortic valve replacement
Content Type	Text
Resource Type	Article
Subject	Pulmonary and Respiratory Medicine Surgery Cardiology and Cardiovascular Medicine