Osteoporosis therapies and their mechanisms of action (Review).

Content Provider	Europe PMC
Author	Kim, Beomchang Cho, Yong Jin Lim, Wonbong
Copyright Year	2020
Abstract	Osteoporosis is a common disease that affects millions of patients worldwide and is most common in menopausal women. The main characteristics of osteoporosis are low bone density and increased risk of fractures due to deterioration of the bone architecture. Osteoporosis is a chronic disease that is difficult to treat; thus, investigations into novel effective therapeutic methods are required. A number of studies have focused on determining the most effective treatment options for this disease. There are several treatment options for osteoporosis that differ depending on the characteristics of the disease, and these include both well-established and newly developed drugs. The present review focuses on the various drugs available for osteoporosis, the associated mechanisms of action and the methods of administration.
ISSN	17920981
Journal	Experimental and Therapeutic Medicine
Volume Number	22
PubMed Central reference number	PMC8506919
Issue Number	6
PubMed reference number	34650627
e-ISSN	17921015
DOI	10.3892/etm.2021.10815
Language	English
Publisher	D.A. Spandidos
Publisher Date	2021-09-28
Access Restriction	Open
Rights License	This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made. Copyright: © Kim et al.
Subject Keyword	osteoporosis treatment osteoblast osteoclast bone resorption bone formation bone remodeling menopause fracture
Content Type	Text
Resource Type	Article
Subject	Immunology and Microbiology Cancer Research