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Peritoneal dialysis in Tunisia: complications, technique and patient's survival (twenty-seven years of experience in a single center).
| Content Provider | Europe PMC |
|---|---|
| Author | Salem, Meriem Ben Ayed, Amel Taieb, Sahbi Khaled Handous, Insaf Saleh, Manel Ben Hamouda, Mouna Letaief, Ahmed Aloui, Sabra Skhiri, Habib |
| Copyright Year | 2021 |
| Abstract | Introductionperitoneal dialysis (PD) is a renal replacement therapy method that offers various advantages to end-stage renal disease patients. The aim of our study was to analyze patient characteristics, peritonitis and clinical outcome over a 27-year period of PD in our center.Methodsretrospective study of incident patients on PD from January 1990 to December 2017. A total of 304 patients were enrolled in the study group. All patients over 15 years of age entering the dialysis program were included in the study. Patients dropping out from PD within three months were all excluded. Biochemical and demographic variables, peritonitis episodes and patient and technique survival were analyzed.Resultsthe PD prevalence in our center was 4.5% during the study period; the mean age was 46.47 ± 18.6 years; diabetic nephropathy was the main cause of chronic kidney disease: 35.5% (n=108). Cardiovascular disease was the main cause of death: 39.6% (n=34). The peritonitis rate was 0.68 episode per patient-year. Ultrafiltration failure was the most important cause of PD withdrawal: 43% (n=60). Occurrence of peritonitis was the only independent predictor of technique failure: adjusted relative risk [aRR] 5.07, 95% CI 2.69-9.58; p<0.001. The overall non-adjusted patient survival was around 100%, 95% and less than 20% at 1, 4 and 25 years respectively basing on the Kaplan-Meier analysis. The group undergoing renal transplantation had the best survival rate.Conclusionperitonitis remains the most common complication as well as the most provider of technique failure and patient´s transfer to hemodialysis. The technique survival was better in case of absence of peritonitis. However, our series showed the superiority of hemodialysis over PD in terms of overall patient survival. |
| Journal | The Pan African Medical Journal |
| Volume Number | 39 |
| PubMed Central reference number | PMC8449580 |
| PubMed reference number | 34584605 |
| e-ISSN | 19378688 |
| DOI | 10.11604/pamj.2021.39.179.29354 |
| Language | English |
| Publisher | The African Field Epidemiology Network |
| Publisher Date | 2021-07-07 |
| Access Restriction | Open |
| Rights License | The Pan African Medical Journal (ISSN: 1937-8688). This is an Open Access article distributed under the terms of the Creative Commons Attribution International 4.0 License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Copyright: Meriem Ben Salem et al. |
| Subject Keyword | Peritoneal dialysis peritonitis patient survival technique survival |
| Content Type | Text |
| Resource Type | Article |
| Subject | Medicine |
