Efficacy of eHealth Interventions for Adults with Diabetes: A Systematic Review and Meta-Analysis.

Content Provider	Europe PMC
Author	Bassi, Giulia Mancinelli, Elisa Dell’Arciprete, Gaia Rizzi, Silvia Gabrielli, Silvia Salcuni, Silvia
Editor	Tchounwou, Paul B.
Copyright Year	2021
Abstract	The aim is to provide meta-analytical evidence on eHealth interventions' efficacy in supporting the psychosocial and physical well-being of adults with type 1 or type 2 Diabetes Mellitus (DM), and to investigate differences in interventions primarily targeted at providing glycemic control vs. psychosocial support. A PRISMA-guided systematic search was conducted. Randomized Controlled Trials (RCTs) regarding eHealth interventions for adults (18-65 years) with DM were included. Data were pooled using Standard Mean Difference (SMD); sub-group analysis and meta-regressions were performed when appropriate. Outcomes were Hemoglobin A1c (HbA1c), diabetes distress, quality of life, anxiety, stress, and depression. Intervention acceptability was assessed performing the Odds Ratio (OR) of drop-out rates. Thirteen RCTs comprising 1315 participants were included (52.09% females; Mage = 46.18, SD = 9.98). Analyses showed intervention efficacy on HbA1c (SMD = -0.40; 95% CI = -0.70, -0.12; k = 13) and depressive symptoms (SMD = -0.18; 95% CI = -0.33, -0.02; k = 6) at RCTs endpoint and were well accepted (OR = 1.43; 95% CI = 0.72, 2.81; k = 10). However, efficacy on HbA1c was not maintained at follow-up (SMD = -0.13; 95% CI = -0.31, 0.05; k = 6). eHealth interventions providing medical support were acceptable and effective in fostering glycemic control and decreasing depressive symptoms in the short-term only. Digital solutions should be developed on multiple levels to fully support the psychophysical well-being of people with DM.
ISSN	16617827
Journal	International Journal of Environmental Research and Public Health [Int J Environ Res Public Health]
Volume Number	18
DOI	10.3390/ijerph18178982
PubMed Central reference number	PMC8431552
Issue Number	17
PubMed reference number	34501572
e-ISSN	16604601
Language	English
Publisher	Molecular Diversity Preservation International (MDPI)
Publisher Date	2021-08-26
Access Restriction	Open
Subject Keyword	diabetes mellitus eHealth psychosocial factors HbA1c meta-analysis
Content Type	Text
Resource Type	Article
Subject	Health, Toxicology and Mutagenesis Pollution Public Health, Environmental and Occupational Health