NDLI: Diabetes and pancreatic cancer: Exploring the two-way traffic.

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Diabetes and pancreatic cancer: Exploring the two-way traffic.

Content Provider	Europe PMC
Author	Roy, Ayan Sahoo, Jayaprakash Kamalanathan, Sadishkumar Naik, Dukhabandhu Mohan, Pazhanivel Kalayarasan, Raja
Copyright Year	2021
Abstract	Pancreatic cancer (PC) is often associated with a poor prognosis. Long-standing diabetes mellitus is considered as an important risk factor for its development. This risk can be modified by the use of certain antidiabetic medications. On the other hand, new-onset diabetes can signal towards an underlying PC in the elderly population. Recently, several attempts have been made to develop an effective clinical tool for PC screening using a combination of history of new-onset diabetes and several other clinical and biochemical markers. On the contrary, diabetes affects the survival after treatment for PC. We describe this intimate and complex two-way relationship of diabetes and PC in this review by exploring the underlying pathogenesis.
ISSN	10079327
Volume Number	27
PubMed Central reference number	PMC8384733
Issue Number	30
PubMed reference number	34497428
Journal	World Journal of Gastroenterology [World J. Gastroenterol]
e-ISSN	22192840
DOI	10.3748/wjg.v27.i30.4939
Language	English
Publisher	Baishideng Publishing Group Inc
Publisher Date	2021-08-01
Access Restriction	Open
Rights License	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
Subject Keyword	Chronic pancreatitis Diabetes New onset diabetes Pancreatic adenocarcinoma Pancreatic cancer Type 3c diabetes
Content Type	Text
Resource Type	Article
Subject	Gastroenterology

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