The Association between Behavioral Risk Factors and Nontuberculous Mycobacterial Pulmonary Disease.

Content Provider	Europe PMC
Author	Park, Youngmok Kwak, Se Hyun Yong, Seung Hyun Lee, Su Hwan Leem, Ah Young Kim, Song Yee Lee, Sang Hoon Chung, Kyungsoo Kim, Eun Young Jung, Ji Ye Park, Moo Suk Kim, Young Sam Chang, Joon Kang, Young Ae
Copyright Year	2021
Abstract	PurposeWe aimed to determine the relationship between environmental exposure and nontuberculous mycobacterial pulmonary disease (NTM-PD) in Korea.Materials and MethodsA group of 150 patients with NTM-PD and a control group of 217 patients with other respiratory diseases were prospectively enrolled between June 2018 and December 2020 in Seoul, Korea. They were surveyed with a standardized questionnaire, and their medical records were reviewed. Odds ratio (OR) and 95% confidence intervals (CI) were calculated with multivariate logistic regression analysis.ResultsThe mean ages of the NTM-PD and control groups were similar (63.8±9.2 years vs. 63.5±10.0 years; p=0.737), and most patients were female (76.0% vs. 68.7%; p=0.157) and nonsmokers (82.0% vs. 72.8%; p=0.021). Mycobacterium avium (49.3%) was the most commonly identified strain among NTM-PD patients, followed by M. intracellulare (32.0%) and M. abscessus subspecies massiliense (12.7%). There were no differences in housing type or frequency of soil- or pet-related exposure between the case and the control groups. However, in subgroup analysis excluding patients with M. intracellulare infection, more case patients frequently visited public baths ≥1 time/week (35.3% vs. 19.4%, p=0.003); this remained significant after multivariate analysis (OR, 2.84; 95% CI, 1.58–5.17).ConclusionFrequent exposure to water at public baths might affect the odds of contracting NTM-PD, excluding individuals infected with M. intracellulare strains.
ISSN	05135796
Volume Number	62
PubMed Central reference number	PMC8298869
Issue Number	8
PubMed reference number	34296547
Journal	Yonsei Medical Journal [Yonsei Med. J]
e-ISSN	19762437
DOI	10.3349/ymj.2021.62.8.702
Language	English
Publisher	Yonsei University College of Medicine
Publisher Date	2021-08-01
Access Restriction	Open
Rights License	This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. © Copyright: Yonsei University College of Medicine 2021
Subject Keyword	Nontuberculous mycobacteria nontuberculous mycobacterium infection environmental exposure
Content Type	Text
Resource Type	Article
Subject	Medicine