Undifferentiated Pancreatic Carcinoma With Osteoclast-Like Giant Cells and Associated Ductal Adenocarcinoma With Focal Signet-Ring Features.

Content Provider	Europe PMC
Author	Olayinka, Oluwaseyi Kaur, Gagandeep Gupta, Gunjan
Editor	Muacevic, Alexander Adler, John R
Copyright Year	2021
Abstract	Undifferentiated pancreatic carcinoma with osteoclast-like giant cells (UPC-OGC) is a unique and rare tumor characterized by the presence of highly atypical carcinoma cells and non-neoplastic osteoclast-like giant cells. The histogenesis of this tumor is unclear and data on its prognosis remain controversial. Some data show poor clinical outcomes in affected patients while other more recent studies report a better outcome especially for cases with pure UPC-OGC. There are currently no established reliable management guidelines for UPC-OGC partly because of its rarity and presence of conflicting data in the literature. Hence the need for continued reporting and further research on this neoplasm. We report an incidental finding of UPC-OGC with associated ductal adenocarcinoma and focal signet ring features in an elderly male patient who presented with symptoms of urinary tract infection (UTI).
Journal	Cureus
Volume Number	13
DOI	10.7759/cureus.14988
PubMed Central reference number	PMC8195551
Issue Number	5
PubMed reference number	34131533
e-ISSN	21688184
Language	English
Publisher	Cureus
Publisher Date	2021-05-12
Publisher Place	Palo Alto (CA)
Access Restriction	Open
Subject Keyword	carcinoma pancreas undifferentiated carcinoma osteoclast-like giant cells case report ductal adenocarcinoma variant
Content Type	Text
Resource Type	Case study
Subject	Medicine