Research progress in decellularized extracellular matrix-derived hydrogels.

Content Provider	Europe PMC
Author	Zhang, Wenhui Du, Aoling Liu, Shun Lv, Mingyue Chen, Shenghua
Copyright Year	2021
Abstract	Decellularized extracellular matrix (dECM) is widely used in regenerative medicine as a scaffold material due to its unique biological activity and good biocompatibility. Hydrogel is a three-dimensional network structure polymer with high water content and high swelling that can simulate the water environment of human tissues, has good biocompatibility, and can exchange nutrients, oxygen, and waste with cells. At present, hydrogel is the ideal biological material for tissue engineering. In recent years, rapid development of the hydrogel theory and technology and progress in the use of dECM to form hydrogels have attracted considerable attention to dECM hydrogels as an innovative method for tissue engineering and regenerative medicine. This article introduces the classification of hydrogels, and focuses on the history and formation of dECM hydrogels, the source of dECM, the application of dECM hydrogels in tissue engineering and the commercial application of dECM materials.
Related Links	https://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC8142036&blobtype=pdf
Journal	Regenerative Therapy [Regen Ther]
Volume Number	18
DOI	10.1016/j.reth.2021.04.002
PubMed Central reference number	PMC8142036
PubMed reference number	34095366
e-ISSN	23523204
Language	English
Publisher	Japanese Society for Regenerative Medicine
Publisher Date	2021-05-18
Access Restriction	Open
Rights License	This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). © 2021 The Japanese Society for Regenerative Medicine. Production and hosting by Elsevier B.V.
Subject Keyword	Decellularization Extracellular matrix Hydrogel Tissue engineering Regenerative medicine
Content Type	Text
Resource Type	Article
Subject	Developmental Biology Biomaterials Biomedical Engineering