NDLI: Histopathology of IBD Colitis. A practical approach from the pathologists of the Italian Group for the study of the gastrointestinal tract (GIPAD).

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Histopathology of IBD Colitis. A practical approach from the pathologists of the Italian Group for the study of the gastrointestinal tract (GIPAD).

Content Provider	Europe PMC
Author	Villanacci, Vincenzo Reggiani-Bonetti, Luca Salviato, Tiziana Leoncini, Giuseppe Cadei, Moris Albarello, Luca Caputo, Alessandro Aquilano, Maria Costanza Battista, Serena Parente, Paola
Copyright Year	2021
Abstract	SummaryInflammatory bowel diseases (IBDs) are lifelong disorders in which an interaction between genetic and environmental factors is involved. IBDs include two entities: Crohn’s disease (CD) and ulcerative colitis (UC); these can be adequately diagnosed and distinguished with a correct methodological approach based on communicating exhaustive clinical, endoscopic and laboratory information to the pathologist and performing adequate bioptic sampling and precise morphological signs including crypt architecture, distribution of inflammation and granulomas, when present. IBD needs to be distinguished from non-IBD colitis, mostly at its onset. Moreover, IBDs are associated with an increased risk of developing colorectal adenocarcinoma. In daily pathological practice, correct diagnosis of IBD and its subclassification as well as a correct detection of dysplasia is imperative to establish the best therapeutic approach.
Related Links	https://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC8138698&blobtype=pdf
Page Count	15
ISSN	00312983
Journal	Pathologica
Volume Number	113
PubMed Central reference number	PMC8138698
Issue Number	1
PubMed reference number	33686309
e-ISSN	1591951X
DOI	10.32074/1591-951x-235
Language	English
Publisher	Pacini Editore srl
Publisher Date	2021-02-01
Access Restriction	Open
Rights License	This is an open access journal distributed in accordance with the CC-BY-NC-ND (Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International) license: the work can be used by mentioning the author and the license, but only for non-commercial purposes and only in the original version. For further information: https://creativecommons.org/licenses/by-nc-nd/4.0/deed.en © 2021 Copyright by Società Italiana di Anatomia Patologica e Citopatologia Diagnostica, Divisione Italiana della International Academy of Pathology
Subject Keyword	inflammatory bowel disease ulcerative colitis Crohn’s disease dysplasia intestinal cancer
Content Type	Text
Resource Type	Article
Subject	Pathology and Forensic Medicine

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