A recently explored aspect of the iceberg named COVID-19: multisystem inflammatory syndrome in children (MIS-C).

Content Provider	Europe PMC
Author	Haslak, Fatih Yıldız, Mehmet Adrovic, Amra Şahin, Sezgin Barut, Kenan Kasapçopur, Özgür
Copyright Year	2021
Abstract	Humanity has recently gained a novel foe named coronavirus disease 2019. Although data so far mostly suggest that children are more likely to have a favorable disease course, new concerns have been raised because of recently reported pediatric cases with hyperinflammatory conditions resembling Kawasaki disease, toxic shock syndrome, and macrophage activation syndrome/hemophagocytic lymphohistiocytosis. Because the increasing evidence suggests that this recent hyperinflammatory condition emerged in the coronavirus disease 2019 era is a distinct clinical picture, the Centers for Disease Control and Prevention named this novel disease multisystem inflammatory syndrome in children. Even if this novel disease is rare, it seems to be highly fatal. Therefore, it is urgent to understand the pathogenesis of the disease to be able to establish the appropriate treatment regimes. Concerns regarding the diagnostic process and the management of the disease have been raised even among pediatricians. Therefore, we aimed to clarify this newly occurring enigma based on the current literature and our clinical insights.
Related Links	https://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC8114613&blobtype=pdf
Journal	Turkish Archives of Pediatrics [Turk Arch Pediatr]
Volume Number	56
PubMed Central reference number	PMC8114613
Issue Number	1
PubMed reference number	34013222
e-ISSN	27576256
DOI	10.5152/turkarchpediatr.2020.20245
Language	English
Publisher	Turkish Pediatric Association
Publisher Date	2021-01-01
Access Restriction	Open
Rights License	Content of this journal is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. Copyright © 2021 Turkish Pediatric Association
Subject Keyword	Coronavirus disease 2019 (COVID-19) hyperinflammatory syndrome toxic shock syndrome Kawasaki disease multisystem inflammatory syndrome in children (MIS-C) pediatric inflammatory multisystem syndrome temporally associated with severe acute respiratory syndrome coronavirus 2 infection (PIMS-TS) pediatrics severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Content Type	Text
Resource Type	Article
Subject	Pediatrics, Perinatology and Child Health