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A Case of Generalized Lichen Sclerosus et Atrophicus.
| Content Provider | Europe PMC |
|---|---|
| Author | Hong, Eun Hye An, Min Kyun Cho, Eun Byul Park, Eun Joo Kim, Kwang Joong Kim, Kwang Ho |
| Copyright Year | 2020 |
| Abstract | A 62-year-old female, with previous history of asthma and hypertension, presented with generalized hyperpigmented skin lesion, found a year ago. Physical examination revealed brown colored lichenified and sclerotic patches on the lower abdomen and flexural areas of extremities. Punch biopsy was performed and histopathological examination revealed hyperkeratosis, follicular plugging and thinning in epidermis. In dermoepidermal junction, cleft like space separating atrophic epidermis and dermis was seen. Also, lichenoid lymphocytic infiltration was observed in mid-dermis. Based on clinical and histopathological findings, a diagnosis of generlaized lichen sclerosus et atrophicus (LSA) was made. Other laboratory examinations were unremarkable. As there is no standard treatment for LSA, the patient received various treatments including topical steroid, tacrolimus and narrow-band ultraviolet B therapy. The skin lesion has softened and its color improved after treatment. LSA is defined as infrequent chronic inflammatory dermatosis with anogenital and extragenital manifestations. Generalized type is rare and genital involvement is the most frequent and often the only site of involvement. We report this case as it is an uncommon type of LSA with generalized hyperpigmented and sclerotic skin lesion in a postmenopausal female patient. |
| ISSN | 10139087 |
| Journal | Annals of Dermatology |
| Volume Number | 32 |
| PubMed Central reference number | PMC7992656 |
| Issue Number | 4 |
| PubMed reference number | 33911760 |
| e-ISSN | 20053894 |
| DOI | 10.5021/ad.2020.32.4.327 |
| Language | English |
| Publisher | The Korean Dermatological Association; The Korean Society for Investigative Dermatology |
| Publisher Date | 2020-06-30 |
| Access Restriction | Open |
| Rights License | This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. Copyright © 2020 The Korean Dermatological Association and The Korean Society for Investigative Dermatology |
| Subject Keyword | Generalized Lichen sclerosus et atrophicus |
| Content Type | Text |
| Resource Type | Article |
| Subject | Dermatology |
