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Pulmonary hypertension in connective tissue diseases, new evidence and challenges.
| Content Provider | Europe PMC |
|---|---|
| Author | Vonk, Madelon C. Vandecasteele, Els van Dijk, Arie P. |
| Abstract | AbstractPulmonary arterial hypertension is a lethal complication of different connective tissue diseases such as systemic sclerosis, mixed connective tissue disease and systemic lupus erythematosus. Although the treatment possibilities for patients with pulmonary arterial hypertension have increased in the last two decades and survival of patients with idiopathic pulmonary arterial hypertension has improved, the latter is not the case for patients with pulmonary arterial hypertension associated with connective tissue disease. In this narrative review, we review recent literature and describe the improvement of early diagnostic possibilities, screening modalities and treatment options. We also point out the pitfalls in diagnosis in this patient category and describe the unmet needs and what the focus of future research should be. |
| Related Links | https://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC7988614&blobtype=pdf |
| Page Count | 12 |
| ISSN | 00142972 |
| Journal | European Journal of Clinical Investigation [Eur J Clin Invest] |
| Volume Number | 51 |
| DOI | 10.1111/eci.13453 |
| PubMed Central reference number | PMC7988614 |
| Issue Number | 4 |
| PubMed reference number | 33216992 |
| e-ISSN | 13652362 |
| Language | English |
| Publisher | John Wiley and Sons Inc. |
| Publisher Date | 2020-12-05 |
| Publisher Place | Hoboken |
| Access Restriction | Open |
| Rights License | This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. © 22020 The Authors. European Journal of Clinical Investigation published by John Wiley & Sons Ltd on behalf of Stichting European Society for Clinical Investigation Journal Foundation |
| Subject Keyword | connective tissue disease pulmonary hypertension systemic lupus erythematosus systemic sclerosis |
| Content Type | Text |
| Resource Type | Article |
| Subject | Medicine Clinical Biochemistry Biochemistry |
